Benzophenone semicarbazone

Base Information

• Chemical Name: Benzophenone semicarbazone
• CAS No.: 14066-73-0
• Molecular Formula: C14H13 N3 O
• Molecular Weight: 239.277
• NSC Number: 99833
• DSSTox Substance ID: DTXSID60295132
• Nikkaji Number: J556.267H
• ChEMBL ID: CHEMBL74465
• Mol file: 14066-73-0.mol

Synonyms:Benzophenone semicarbazone;14066-73-0;NSC99833;Diphenylsemicarbazone;Benzophenoneimine N-ureido-;NCIOpen2_007263;CHEMBL74465;Diphenylmethanone semicarbazone #;DTXSID60295132;GTQVKKKKXODXQZ-UHFFFAOYSA-N;NSC-99833

Chemical Property of Benzophenone semicarbazone

Chemical Property:

• Density: 1.17g/cm³
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 239.105862047
• Heavy Atom Count: 18
• Complexity: 282

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=NNC(=O)N)C2=CC=CC=C2

Technology Process of Benzophenone semicarbazone

There total 4 articles about Benzophenone semicarbazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(2,5-dioxopyrrolidin-1-yl)-N'-(diphenylmethylidene) carbazate (1513924-93-0) → benzophenone semicarbazone (14066-73-0)

Guidance literature:

1-(2,5-dioxopyrrolidin-1-yl)-N'-(diphenylmethylidene) carbazate; With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 16h;

With triethylsilane; trifluoroacetic acid; In water;

DOI:10.1002/psc.2711

Reference yield:

benzophenone (119-61-9) + semicarbazide hydrochloride (563-41-7) → benzophenone semicarbazone (14066-73-0)

Guidance literature:

With ethanol; sodium acetate;

Reference yield:

Benzophenone imine (1013-88-3) + hydrazine carboxamide (4426-72-6,51433-48-8,57-56-7) → benzophenone semicarbazone (14066-73-0)

Guidance literature:

upstream raw materials:

benzophenone

semicarbazide hydrochloride

Benzophenone imine

hydrazine carboxamide

Downstream raw materials:

N,N'-dibenzhydryl-urea

benzhydrylurea

Benzophenon-4-benzhydryl-semicarbazon

benzophenone hydrazone

Refernces

• 1、 Vahedi,Lari,Bavand,Ameri. "Cyclization of the semicarbazones to 1,3,4-oxadiazole derivatives using ceric ammonium nitrate as oxidant". experimental part. p. 288 - 290. Retrieved 2012/08/08.