4-BROMO-2,3,5,6-TETRAFLUOROBENZOTRIFLUORIDE

Base Information

• Chemical Name: 4-BROMO-2,3,5,6-TETRAFLUOROBENZOTRIFLUORIDE
• CAS No.: 17823-46-0
• Molecular Formula: C7BrF7
• Molecular Weight: 296.97
• Hs Code.: 29039990
• Mol file: 17823-46-0.mol

Synonyms:4-Bromoperfluorotoluene;Toluene,4-bromoheptafluoro- (8CI);1-Bromo-2,3,5,6-tetrafluoro-4-(trifluoromethyl)benzene;2,3,5,6-Tetrafluoro-4-trifluoromethylbromobenzene;3-Bromo-1,2,4,5-tetrafluoro-6-(trifluoromethyl)benzene;4-Bromoheptafluorotoluene;

Chemical Property of 4-BROMO-2,3,5,6-TETRAFLUOROBENZOTRIFLUORIDE

Chemical Property:

• Appearance/Colour: clear colorless liquid
• Vapor Pressure: 4.46mmHg at 25°C
• Refractive Index: n20/D 1.429(lit.)
• Boiling Point: 152.5 °C at 760 mmHg
• Flash Point: 62.8 °C
• PSA: 0.00000
• Density: 1.904 g/cm³
• LogP: 4.02430
• Storage Temp.: 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Bromo-2,3,5,6-tetrafluorobenzotrifluoride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-BROMO-2,3,5,6-TETRAFLUOROBENZOTRIFLUORIDE

There total 8 articles about 4-BROMO-2,3,5,6-TETRAFLUOROBENZOTRIFLUORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

4-trifluoromethyl-2,3,5,6-tetrafluorothiophenol (651-84-3) → 4-trifluoromethyl-2,3,5,6-tetrafluorobromobenzene (17823-46-0)

Guidance literature:

With bromine; at 500 ℃;

DOI:10.1007/s11178-006-0012-1

Reference yield: 90.0%

perfluorotoluene (434-64-0) → 4-trifluoromethyl-2,3,5,6-tetrafluorobromobenzene (17823-46-0)

Guidance literature:

perfluorotoluene; With stannous fluoride; zinc; In N,N-dimethyl-formamide; at 70 ℃; for 8h; closed flask;

With bromine; N,N-dimethyl-formamide; steam distillation;

DOI:10.1070/MC2006v016n03ABEH002266

Reference yield: 82.0%

nBu4N+[Cu(2,3,5,6-tetrafluoro-4-bromophenyl)(CF3)3]- → 4-trifluoromethyl-2,3,5,6-tetrafluorobromobenzene (17823-46-0)

Guidance literature:

In 1,2-dichloro-ethane; at 95 ℃; Kinetics; Glovebox; Inert atmosphere;

DOI:10.1002/anie.201904041

upstream raw materials:

1,2,4,5-tetrafluoro-3-(trifluoromethyl)benzene

perfluorotoluene

4-trifluoromethyl-2,3,5,6-tetrafluorothiophenol

bromopentafluorobenzene

Downstream raw materials:

2,3,5,6-tetrafluoro-4-(trifluoromethyl)benzaldehyde

trimethyl(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)silane

tris(4-trifluoromethyl-2,3,5,6-tetrafluorophenyl)phosphine

Refernces

• 1、 Cherstkov, V. F.,Sterlin, S. R.,German, L. S.. "AN UNUSUAL REACTION OF PERFLUOROTOLUENE WITH ALUMINUM BROMIDE". . p. 2452. Retrieved 1985.
• 2、 Krasnov, Vyacheslav I.,Vinogradov, Andrey S.,Platonov, Vyacheslav E.. "Preparation of organozinc compounds from 3-chloroheptafluorotoluene and zinc: The participation of C-F bonds". . p. 168 - 170. Retrieved 2007/10/03.