(R)-2-((tert-Butoxycarbonyl)amino)-4,4-dimethylpentanoic acid

Base Information Edit

Chemical Name:(R)-2-((tert-Butoxycarbonyl)amino)-4,4-dimethylpentanoic acid
CAS No.:112695-98-4
Molecular Formula:C12H23 N O4
Molecular Weight:245.319
Hs Code.:
DSSTox Substance ID:DTXSID40427333
Mol file:112695-98-4.mol

Synonyms:112695-98-4;Boc-beta-t-butyl-D-alanine;(R)-2-((tert-Butoxycarbonyl)amino)-4,4-dimethylpentanoic acid;Boc-D-NptGly-OH;Boc-D-neopentylglycine;(2R)-4,4-dimethyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoic acid;BOC-BETA-TBU-D-ALA-OH;(2R)-2-{[(tert-butoxy)carbonyl]amino}-4,4-dimethylpentanoic acid;boc-d-ala(tbu)-oh;Boc-D-t-butyl-alanine;Boc--tBu-D-Ala-OH;Boc-D-tert-butyl-alanine;Boc-b-tert-butyl-D-alanine;SCHEMBL1360500;DTXSID40427333;PUQVQDMFCAGQQB-MRVPVSSYSA-N;CS-M3461;HY-79404A;MFCD00798621;AKOS015836516;CS-13446;N-(tert-butoxycarbonyl)-4-methyl-D-leucine;N-tert-Butoxycarbonyl-3-tert-butyl-D-alanine;EN300-6472514;N-(tert-Butoxycarbonyl)-3-tert-butyl-D-alanine;A894534;N2-(tert-Butoxycarbonyl)-3-tert-butyl-D-alanine;Boc-D-Neopentylgly-OH;Boc--Me-D-Leu-OH;Boc-D-Tba-OH;D-Leucine,N-[(1,1-dimethylethoxy)carbonyl]-4-methyl-;(R)-2-((tert-Butoxycarbonyl)amino)-4,4-dimethylpentanoicacid

Suppliers and Price of (R)-2-((tert-Butoxycarbonyl)amino)-4,4-dimethylpentanoic acid

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Boc-D-neopentylglycine
50mg
$ 333.00

TRC
Boc-β-t-butyl-d-alanine
25mg
$ 75.00

Matrix Scientific
Boc-beta-t-butyl-D-alanine
250mg
$ 200.00

Matrix Scientific
Boc-beta-t-butyl-D-alanine
500mg
$ 325.00

Matrix Scientific
Boc-beta-t-butyl-D-alanine
1g
$ 500.00

Iris Biotech GmbH
Boc-D-NptGly-OH
1 g
$ 506.25

Iris Biotech GmbH
Boc-D-NptGly-OH
5 g
$ 1890.00

Crysdot
(R)-2-((tert-Butoxycarbonyl)amino)-4,4-dimethylpentanoicacid 95+%
5g
$ 1409.00

Crysdot
(R)-2-((tert-Butoxycarbonyl)amino)-4,4-dimethylpentanoicacid 95+%
1g
$ 325.00

ChemScene
(R)-2-tert-Butoxycarbonylamino-4,4-dimethylpentanoicacid
1g
$ 350.00

Total 25 raw suppliers

Chemical Property of (R)-2-((tert-Butoxycarbonyl)amino)-4,4-dimethylpentanoic acid Edit

Chemical Property:

Boiling Point:364.4±25.0 °C(Predicted)
PKA:4.03±0.23(Predicted)
PSA：75.63000
Density:1.048±0.06 g/cm3 (20 ºC 760 Torr)
LogP:2.79140
Storage Temp.:Store at RT.
XLogP3:2.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:245.16270821
Heavy Atom Count:17
Complexity:286

Purity/Quality:

98%, ^*data from raw suppliers

Boc-D-neopentylglycine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)CC(C(=O)O)NC(=O)OC(C)(C)C
Isomeric SMILES:CC(C)(C)C[C@H](C(=O)O)NC(=O)OC(C)(C)C
Uses Boc-beta-t-butyl-d-alanine is a useful intermediate in the synthesis of peptides and other amino acids.

Technology Process of (R)-2-((tert-Butoxycarbonyl)amino)-4,4-dimethylpentanoic acid

There total 33 articles about (R)-2-((tert-Butoxycarbonyl)amino)-4,4-dimethylpentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.5%

: 24424-99-5
di-tert-butyl dicarbonate

: 88319-43-1
(R)-2-amino-4,4-dimethylpentanoic acid

: 112695-98-4
(2R)-2-{[(tert-butoxy)carbonyl]amino}-4,4-dimethylpentanoic acid

Guidance literature:: di-tert-butyl dicarbonate; (R)-2-amino-4,4-dimethylpentanoic acid; With sodium hydroxide; In tetrahydrofuran; water; at 20 ℃;

With sodium hydrogen sulfate; In tetrahydrofuran; water;