1,1'-Bis(diisopropylphosphino)ferrocene

Base Information

• Chemical Name: 1,1'-Bis(diisopropylphosphino)ferrocene
• CAS No.: 97239-80-0
• Molecular Formula: C22H36FeP2
• Molecular Weight: 418.322
• Hs Code.: 29319090
• Mol file: 97239-80-0.mol

Synonyms:1,1'-Bis(diisopropylphosphino)ferrocene;

Chemical Property of 1,1'-Bis(diisopropylphosphino)ferrocene

Chemical Property:

• Appearance/Colour: orange crystalline powder
• Melting Point: 50-52 °C(lit.)
• Flash Point: >230°F
• PSA: 27.18000
• LogP: 6.72050
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Water Solubility.: Insoluble in water.

Purity/Quality:

98%, ^*data from raw suppliers

1,1-Bis(diisopropylphosphino)ferrocene ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 37/39-26

MSDS Files:

SDS file from LookChem

Useful:

• Uses: The general and efficient cross-coupling of thiols with aryl halides was developed utilizing Pd(OAc) 2 /1,1?-bis(diisopropylphosphino)ferrocene as the catalyst. The oxidative electrochemistry of dippf was examined, and it was found to follow an ECDim mechanism. Seven new compounds containing dippf were prepared and characterized spectroscopically. The crystal structures of [MCl2(dippf)] (M = Pt and Zn) were determined.

Technology Process of 1,1'-Bis(diisopropylphosphino)ferrocene

There total 3 articles about 1,1'-Bis(diisopropylphosphino)ferrocene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

1,1'-bis(diisopropylphosphino)ferrocene tetrafluoroborate → 1,1'-bis(diisopropylphosphino)ferrocene (97239-80-0)

Guidance literature:

In methanol; for 12h; Reflux;

Reference yield: 58.0%

1,1'-dilithioferrocene N,N,N'N'-tetramethylethylenediamine + Chlorodiisopropylphosphane (40244-90-4) → 1,1'-bis(diisopropylphosphino)ferrocene (97239-80-0)

Guidance literature:

In hexane; phosphine (2 equiv.) added dropwise at -78°C to Fe complex suspn., stirred for 30 min, warmed slowly to 20°C; hydrolyzed (H2O), org. layer sepd., dried (Na2SO4), solvent removed (vac.), crystd. at 5°C for hours; elem. anal.;

DOI:10.1016/S0022-328X(99)00670-1

Reference yield: 31.0%

1,1‘-bis(diisopropylphosphanyl)magnesocene + iron(II) chloride → 1,1'-bis(diisopropylphosphino)ferrocene (97239-80-0)

Guidance literature:

In tetrahydrofuran; at 20 ℃; Inert atmosphere;

DOI:10.1002/chem.202005198

upstream raw materials:

Chlorodiisopropylphosphane

Downstream raw materials:

dichloro[ferrocene-1,1'-diylbis(diisopropylphosphine-P)]palladium(II)

bromo(4-tert-butylphenyl)(1,1'-bis(di-isopropylphosphino)ferrocene)palladium

((C₆H₅O)2PSN((CH₃)2CH)2PC₅H₄)2Fe

[(η5-C5H4PiPr2)Fe(η5-C5H4PiPr2(C6F4)BF(C6F5)2)]

Refernces

• 1、 -. "A ferrocene diphosphine ligand preparation method". Paragraph 0006; 0019; 0020. . Retrieved 2017/08/31.