SODIUM NITRITE-15N

Base Information

• Chemical Name: SODIUM NITRITE-15N
• CAS No.: 68378-96-1
• Molecular Formula: ¹⁵NNaHO2
• Molecular Weight: 69.9886
• Hs Code.: 28459000
• Mol file: 68378-96-1.mol

Synonyms:Sodium15N-nitrite;Sodium nitrite-15N;

Chemical Property of SODIUM NITRITE-15N

Chemical Property:

• Melting Point: 271 °C(lit.)
• PSA: 52.49000
• LogP: 0.25060

Purity/Quality:

98%min ^*data from raw suppliers

Sodium Nitrite-15N ^*data from reagent suppliers

Safty Information:

• Pictogram(s): O,T,N
• Hazard Codes: O,T,N
• Statements: 8-25-50
• Safety Statements: 45-61

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Labelled analogue of SODIUM NITRITE-15N used in nitrite quantification in human whole blood, erythrocytes, and plasma.

Technology Process of SODIUM NITRITE-15N

There total 2 articles about SODIUM NITRITE-15N which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.5%

sodium (15N)nitrate (31432-45-8) → sodium (15)N-nitrite (68378-96-1)

Guidance literature:

With lead; In neat (no solvent); byproducts: lead oxide; Na(15)NO3 and lead fillings ground in a mortar, stirred and heated at 350°C for 1.5 h on a open flame, cooled, water added, stirred; lead oxide removed by filtration, water distilled off in vacuo, dried in vacuo;

DOI:10.1007/BF00954350

Reference yield:

sodium hydroxide (1310-73-2) + 15N labeled nitric oxide (15917-77-8) → sodium (15)N-nitrite (68378-96-1)

Guidance literature:

In water; with mixture of (15)N-oxides; evaporated in Pt-cup; sucking-off at 0°C; washed with ice-cold methanol;

Reference yield: 80.0%

sodium (15)N-nitrite (68378-96-1) + mer-[(1,4-bis(diphenylphosphino)butane)aquatrichlororuthenium(III)] (243643-58-5) → mer-[RuCl3((15)NO)(1,3-bis(diphenylphosphino)butane)] (897941-64-9,898253-28-6)

Guidance literature:

With HCl; In dichloromethane; (Ar); Na(15)NO2 was added to soln. of Ru complex in CH2Cl2; HCl was added; stirred for 1 h; org. phase septd. and concd.; Et2O added; filtered; washed (H2O); dried (vac.); elem. anal.;

DOI:10.1016/j.ica.2005.12.016

upstream raw materials:

sodium hydroxide

¹⁵N labeled nitric oxide

sodium (¹⁵N)nitrate

Downstream raw materials:

ammonia

dinitrogen monoxide

⁽¹⁵⁾N-nitrogen dioxide

sodium nitrite

Refernces

• 1、 Kostyanovskii, R. G.,Mishchenko, A. I.,Prosyanik, A. V.,Zaichenko, N. L.. "ASYMMETRIC NONBONDED NITROGEN. COMMUNICATION 29. SYNTHESIS AND STUDY OF THE DIMETHYL ESTER OF 15N-ALKOXYAZIRIDINE-2,2-DICARBOXYLIC ACID". . p. 1421 - 1428. Retrieved 2007/10/02.