2,3-Dibromofuran

Base Information

• Chemical Name: 2,3-Dibromofuran
• CAS No.: 30544-34-4
• Molecular Formula: C4H2Br2O
• Molecular Weight: 225.867
• Hs Code.: 2932190090
• European Community (EC) Number: 680-982-0
• DSSTox Substance ID: DTXSID00427379
• Nikkaji Number: J88.671H
• Wikidata: Q82240035
• Mol file: 30544-34-4.mol

Synonyms:2,3-dibromofuran;30544-34-4;Furan, 2,3-dibromo-;2,3-Dibrom-furan;SCHEMBL436685;DTXSID00427379;GKPGEBCMRMQOPF-UHFFFAOYSA-N;MFCD01074839;AKOS022687729;SB60934;AS-75547;CS-0191582;FT-0609521;EN300-115372;A820427

Chemical Property of 2,3-Dibromofuran

Chemical Property:

• Vapor Pressure: 1.53mmHg at 25°C
• Refractive Index: 1.5470
• Boiling Point: 175.6 °C at 760 mmHg
• Flash Point: 60 °C
• PSA: 13.14000
• Density: 2.159 g/cm³
• LogP: 2.80460
• Sensitive.: Light Sensitive
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 225.84519
• Heavy Atom Count: 7
• Complexity: 66.7

Purity/Quality:

98%,99%, ^*data from raw suppliers

2,3-Dibromofuran ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R36/38:Irritating to eyes and skin.
• Hazard Codes: T
• Statements: 36/37/38-41-25-10
• Safety Statements: 26-36/37/39-45-39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=COC(=C1Br)Br

Technology Process of 2,3-Dibromofuran

There total 4 articles about 2,3-Dibromofuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

furfural (98-01-1) → 2,3-dibromofuran (30544-34-4)

Guidance literature:

With aluminium trichloride; bromine; at 20 ℃; for 16h;

DOI:10.1016/j.tet.2005.03.016

Reference yield: 51.0%

4,5-dibromo-2-furoic acid (2434-03-9) → 2,3-dibromofuran (30544-34-4)

Guidance literature:

With copper; In quinoline; at 180 ℃; for 0.666667h;

DOI:10.1016/S0040-4020(01)85353-9

Reference yield:

2,3,4,5-tetrabromo-tetrahydro-furan-2-carboxylic acid (89284-17-3) → 2,3-dibromofuran (30544-34-4) + 5-bromo-furan-2-carboxylic acid (585-70-6) + 3,4-dibromo-furan-2-carboxylic acid (32460-04-1)

Guidance literature:

upstream raw materials:

4,5-dibromo-2-furoic acid

2,3,4,5-tetrabromo-tetrahydro-furan-2-carboxylic acid

furfural

Downstream raw materials:

4,5-dibromo-2-(diethoxymethyl)-furan

(Ss)-3-bromo-2-(p-tolylsulfinyl)-furane

1-(3-dihydroxyboranyl-furan-2-yl)-ethanone

3-bromo-2-(3,4,5-trimethoxyphenyl)furan

Refernces

• 1、 Bach, Thorsten,Krüger, Lars. "The preparation of 2,3,5-tri- and 2,3-disubstituted furans by regioselective palladium(0)-catalyzed coupling reactions: Application to the syntheses of rosefuran and the F5 furan fatty acid". . p. 2045 - 2057. Retrieved 2007/10/03.