4-(Boc-amino)butyl bromide

Base Information Edit

Chemical Name:4-(Boc-amino)butyl bromide
CAS No.:164365-88-2
Molecular Formula:C9H18 Br N O2
Molecular Weight:252.151
Hs Code.:2924199090
European Community (EC) Number:628-851-9
UNII:KWX42DWP3K
DSSTox Substance ID:DTXSID60446526
Nikkaji Number:J1.141.088J
Wikidata:Q82265197
Mol file:164365-88-2.mol

Synonyms:164365-88-2;4-(Boc-amino)butyl bromide;tert-butyl (4-bromobutyl)carbamate;tert-Butyl N-(4-bromobutyl)carbamate;4-(t-Boc-amino)-1-butyl Bromide;tert-butyl(4-bromobutyl)carbamate;Boc-NH-C4-Br;Carbamic acid, (4-bromobutyl)-, 1,1-dimethylethyl ester;tert-Butyl 4-bromobutylcarbamate;MFCD06201020;1,1-dimethylethyl (4-bromobutyl)carbamate;CARBAMIC ACID, N-(4-BROMOBUTYL)-, 1,1-DIMETHYLETHYL ESTER;4-(Boc amino)butyl bromide;KWX42DWP3K;Boc-NH-(CH2)4-Br;N-(tert-Butoxycarbonyl)-1-bromobutan-4-ylamine;N-boc-4-bromobutan-1-amine;N-Boc 4-bromobutan-1-amine;SCHEMBL229087;4-(Boc-amino) Butyl Bromide;N-BOC-4-BROMOBUTYLAMINE;DTXSID60446526;GKGFAEREWWZBKY-UHFFFAOYSA-N;BCP19247;AB6564;AM9905;AKOS015841489;AB23080;CS-W007803;HY-W007803;4-(t-butyloxycarbonylamino)butyl bromide;DS-15335;SY018080;4-bromobutylcarbamic acid tert-butyl ester;tert-Butyl (4-bromobutyl)carbamate, 95%;4-bromobutyl carbamic acid tert-butyl ester;(4-bromobutyl)carbamic acid tert-butyl ester;4-[(tert-Butoxycarbonyl)amino]butyl bromide;FT-0663427;(4-bromobutyl)-carbamic acid tert-butyl ester;(4-bromo-butyl)-carbamic acid tert-butyl ester;EN300-736037;N-(4-Bromobutyl)carbamic acid tert-butyl ester;A1-03088;J-010133;4-(Boc-amino)butyl bromide, technical, >=90% (AT)

Suppliers and Price of 4-(Boc-amino)butyl bromide

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(t-Boc-amino)-1-butylBromide
10g
$ 950.00

TRC
4-(t-Boc-amino)-1-butylBromide
1g
$ 185.00

Sigma-Aldrich
4-(Boc-amino)butyl bromide technical,≥90%(AT)
500 mg
$ 96.10

Sigma-Aldrich
4-(Boc-amino)butyl bromide technical, ≥90% (AT)
500mg-f
$ 91.00

Sigma-Aldrich
4-(Boc-amino)butyl bromide technical,≥90%(AT)
2.5 g
$ 333.00

Sigma-Aldrich
4-(Boc-amino)butyl bromide technical, ≥90% (AT)
2.5g-f
$ 315.00

Matrix Scientific
tert-Butyl 4-bromobutylcarbamate 97%
1g
$ 341.00

Crysdot
tert-Butyl(4-bromobutyl)carbamate 95+%
10g
$ 772.00

Crysdot
tert-Butyl(4-bromobutyl)carbamate 95+%
5g
$ 465.00

Biosynth Carbosynth
4-(t-Boc-amino)-1-butyl bromide
250 mg
$ 125.00

Total 33 raw suppliers

Chemical Property of 4-(Boc-amino)butyl bromide Edit

Chemical Property:

Vapor Pressure:0.000667mmHg at 25°C
Boiling Point:308.8 °C at 760 mmHg
PKA:12.76±0.46(Predicted)
Flash Point:140.5 °C
PSA：38.33000
Density:1.244 g/cm³
LogP:3.07710
Storage Temp.:2-8°C
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:6
Exact Mass:251.05209
Heavy Atom Count:13
Complexity:154

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-(t-Boc-amino)-1-butylBromide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 41
Safety Statements: 26-39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NCCCCBr
Uses 4-(Boc-amino)butyl bromide can be used:For the synthesis of N-Boc-aminoalkoxyphenyl derivatives, precursor to pharmacophore elements for the treatment of glaucoma.For the synthesis of various aloperine derivatives with potential application as anti-HIV agents.For the modification of 4,5,6,7-tetrabromobenzotriazole (TBB) derivatives to generate improved CK2 inhibitors.

Technology Process of 4-(Boc-amino)butyl bromide

There total 11 articles about 4-(Boc-amino)butyl bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 75178-87-9
(4-hydroxybutyl)carbamic acid tert-butyl ester

: 164365-88-2
tert-butyl 4-bromobutylcarbamate

Guidance literature:: With carbon tetrabromide; triphenylphosphine; In tetrahydrofuran; for 3h; Inert atmosphere;
DOI:10.1016/j.bmcl.2011.11.097

Reference yield: 91.0%

: 236101-14-7
N-t-butoxycarbonyl N-4-bromobutyl ethyl oxamate

: 164365-88-2
tert-butyl 4-bromobutylcarbamate

Guidance literature:: With lithium hydroxide; In tetrahydrofuran; water; at 20 ℃; for 3h;
DOI:10.1080/00397919908086430

Reference yield: 80.0%

: 13325-10-5
4-Aminobutanol

: 24424-99-5
di-tert-butyl dicarbonate

: 164365-88-2
tert-butyl 4-bromobutylcarbamate

Guidance literature:: 4-Aminobutanol; di-tert-butyl dicarbonate; With triethylamine; In acetonitrile; at 0 ℃; for 6h;

With carbon tetrabromide; triphenylphosphine; In tetrahydrofuran; for 3h;