beta-D-Galactose pentaacetate

Base Information

• Chemical Name: beta-D-Galactose pentaacetate
• CAS No.: 4163-60-4
• Deprecated CAS: 36116-83-3
• Molecular Formula: C16H22O11
• Molecular Weight: 390.344
• Hs Code.: 29400000
• European Community (EC) Number: 224-008-0
• DSSTox Substance ID: DTXSID20883736
• Nikkaji Number: J109.350I
• Wikidata: Q63409498
• Mol file: 4163-60-4.mol

Synonyms:1,2,3,4,6-penta-O-acetyl-beta-D-galactopyranose;1,2,3,4,6-penta-O-acetylgalactopyranose;beta-penta-O-acetyl-D-galactopyranose

Chemical Property of beta-D-Galactose pentaacetate

Chemical Property:

• Appearance/Colour: white fine crystalline powder
• Vapor Pressure: 9.23E-08mmHg at 25°C
• Melting Point: 143-144 °C(lit.)
• Refractive Index: 23.5 ° (C=2, MeOH)
• Boiling Point: 434.8 °C at 760 mmHg
• Flash Point: 188.1 °C
• PSA: 140.73000
• Density: 1.3 g/cm³
• LogP: -0.36740
• Storage Temp.: −20°C
• Solubility.: methanol: 50 mg/mL, clear
• Water Solubility.: Soluble in methanol (50 mg/ml), chloroform, and water.
• XLogP3: 0.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 11
• Rotatable Bond Count: 11
• Exact Mass: 390.11621151
• Heavy Atom Count: 27
• Complexity: 599

Purity/Quality:

99% ^*data from raw suppliers

1,2,3,4,6-Penta-O-acetyl-b-D-galactopyranose ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 24/25-36/37/39-27-26

MSDS Files:

Useful:

• Canonical SMILES: CC(=O)OCC1C(C(C(C(O1)OC(=O)C)OC(=O)C)OC(=O)C)OC(=O)C
• Isomeric SMILES: CC(=O)OC[C@@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)OC(=O)C)OC(=O)C)OC(=O)C)OC(=O)C

Technology Process of beta-D-Galactose pentaacetate

There total 84 articles about beta-D-Galactose pentaacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

β-D-galactopyranoside (7296-64-2) + acetic anhydride (108-24-7) → β-D-galactose peracetate (4163-60-4)

Guidance literature:

With perchloric acid; In dichloromethane; at 0 ℃; for 1h;

DOI:10.1016/j.bioorg.2021.105479

Reference yield: 100.0%

D-Galactose (59-23-4) + acetic anhydride (108-24-7) → β-D-galactose peracetate (4163-60-4)

Guidance literature:

With pyridine; dmap; at 20 ℃; Inert atmosphere;

DOI:10.1002/chem.201601673

Reference yield: 94.0%

D-Galactose (10257-28-0) + acetic anhydride (108-24-7) → β-D-galactose peracetate (4163-60-4)

Guidance literature:

sulfuric acid; at 20 ℃; for 0.0833333h; sonication;

DOI:10.1021/jo060374w

upstream raw materials:

D-Galactose

acetic anhydride

diazomethane

D-Galactose

Downstream raw materials:

1-O-p-nitrophenyl-2,3,4,6-tetra-O-acetyl α-D-mannopyranoside

ethyl 2,3,4,6-tetra-O-acetyl-1-thio-β-D-mannopyranoside

S-ethyl 2,3,4,6-tetra-O-acetyl-1-deoxy-1-thio-α-D-mannopyranoside

1-O-phenyl-2,3,4,6-tetra-O-acetyl-β-D-mannopyranoside

Refernces

• 1、 Flockton, Tyler R.,Schnorbus, Logan,Araujo, Agustin,Adams, Jill,Hammel, Maryjane,Perez, Lark J.. "Inhibition of pseudomonas aeruginosa biofilm formation with surface modified polymeric nanoparticles". . . Retrieved 2019.
• 2、 Abellán Flos, Marta,García Moreno, M. Isabel,Ortiz Mellet, Carmen,García Fernández, Jose Manuel,Nierengarten, Jean-Francois,Vincent, Stéphane P.. "Potent Glycosidase Inhibition with Heterovalent Fullerenes: Unveiling the Binding Modes Triggering Multivalent Inhibition". . p. 11450 - 11460. Retrieved 2016.
• 3、 Krishnan, Baiju P.,Sureshan, Kana M.. "A spontaneous single-crystal-to-single-crystal polymorphic transition involving major packing changes". . p. 1692 - 1696. Retrieved 2015.
• 4、 -. "PROCESS OF SYNTHESIS OF β-6'SULFOQUINOVOSYL DIACYLGLYCEROLS". Page/Page column 11; 12. . Retrieved 2022/02/28.
• 5、 ?ezanka, Michal,Dolensky, Bohumil,Krabicová, Ilona. "Selectivity of 1-O-Propargyl-D-Mannose Preparations". . . Retrieved 2022/03/01.