Haloxyfop

Base Information

• Chemical Name: Haloxyfop
• CAS No.: 69806-34-4
• Molecular Formula: C15H11 Cl F3 N O4
• Molecular Weight: 361.705
• Hs Code.: 29333990
• European Community (EC) Number: 615-015-3
• UNII: 24TYO6H90H
• DSSTox Substance ID: DTXSID7042019
• Nikkaji Number: J367.068F
• Wikidata: Q27105292
• Metabolomics Workbench ID: 67760
• ChEMBL ID: CHEMBL223593
• Mol file: 69806-34-4.mol

Synonyms:2-(4-((3-chloro-5-(trifluoromethyl)-2-pyridinyl)oxy)phenoxy)propanoic acid;haloxyfop;haloxyfop sodium salt

Chemical Property of Haloxyfop

Chemical Property:

• Vapor Pressure: 8.17E-08mmHg at 25°C
• Melting Point: 107.5 °C
• Boiling Point: 420.3ºC at 760 mmHg
• PKA: 3.12±0.10(Predicted)
• Flash Point: 208 ºC
• PSA: 68.65000
• Density: 1.442 g/cm³
• LogP: 4.39800
• Storage Temp.: 0-6°C
• XLogP3: 4.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 5
• Exact Mass: 361.0328700
• Heavy Atom Count: 24
• Complexity: 429

Purity/Quality:

98%,99%, ^*data from raw suppliers

(±)-Haloxyfop ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C(=O)O)OC1=CC=C(C=C1)OC2=C(C=C(C=N2)C(F)(F)F)Cl
• Uses: (±)-Haloxyfop is a herbicide.

Technology Process of Haloxyfop

There total 6 articles about Haloxyfop which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 2-(4-(3-chloro-5-trifluoromethyl-pyridin-2-yloxy)-phenoxy)-propionate (69806-40-2) → haloxyfop (69806-34-4)

Guidance literature:

With potassium hydroxide; In methanol; water;

Reference yield:

2-(4'-hydroxyphenoxy)-3-chloro-5-trifluoromethylpyridine (69045-89-2) + ethyl (S)-α-(4-methyl-phenylsulphonyloxy)-propionate (33798-77-5) → ethyl D-2-[p-(3-chloro-5-trifluoromethyl-2-pyridyl)oxy]phenoxy]propionate + haloxyfop (69806-34-4)

Guidance literature:

Reference yield:

2-oxopropyl 2-<4-(3-chloro-5-trifluoromethyl-2-pyridinyloxy)phenoxy>propionate (121332-79-4) → haloxyfop (69806-34-4)

Guidance literature:

With methanol; phosphate buffer solution pH 6; at 25 ℃; Rate constant; half-life times; also at pH 7, pH 8;

upstream raw materials:

2-oxopropyl 2-<4-(3-chloro-5-trifluoromethyl-2-pyridinyloxy)phenoxy>propionate

3-hydroxy-2-oxopropyl 2-<4-(3-chloro-5-trifluoromethyl-2-pyridinyloxy)phenoxy>propionate

3-diazo-2-oxopropyl 2-<4-(3-chloro-5-trifluoromethyl-2-pyridinyloxy)phenoxy>propionate

2-(4'-hydroxyphenoxy)-3-chloro-5-trifluoromethylpyridine

Downstream raw materials:

3-bromo-2-oxopropyl 2-<4-(3-chloro-5-trifluoromethyl-2-pyridinyloxy)phenoxy>propionate

2-oxopropyl 2-<4-(3-chloro-5-trifluoromethyl-2-pyridinyloxy)phenoxy>propionate

(3-Acetoxy-2-oxo-)propyl 2-{4-(3-chloro-5-trifluoromethyl-2-pyridyloxy)phenoxy}propionate

2-[4-(5-trifluoromethyl-3-chloro-pyridin-2-yloxy)-phenoxy]propionic acid chloride

Refernces

• 1、 -. "Herbicidally active phenoxyalkanecarboxylic acid derivatives". . . Retrieved 2008/06/13.
• 2、 -. "3-Alkoxy-4-substituted-phenoxy-2,3-unsaturated acid esters and derivatives thereof and the use thereof for the control of weeds". . . Retrieved 2008/06/13.