(s)-4,5,6,7-Tetrahydrobenzo[d]thiazole-2,6-diamine

Base Information Edit

Chemical Name:(s)-4,5,6,7-Tetrahydrobenzo[d]thiazole-2,6-diamine
CAS No.:106092-09-5
Molecular Formula:C7H11N3S
Molecular Weight:169.25
Hs Code.:29349990
European Community (EC) Number:600-715-3
UNII:J4N3Y41JML
ChEMBL ID:CHEMBL1192854
DSSTox Substance ID:DTXSID00893656
Nikkaji Number:J2.844.084G
Wikidata:Q27281199
Mol file:106092-09-5.mol

Synonyms:106092-09-5;(s)-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine;(S)-2,6-Diamino-4,5,6,7-tetrahydrobenzothiazole;(6S)-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine;(S)-N-Despropyl Pramipexole;(s)-4,5,6,7-tetrahydro-2,6-benzothiazolediamine;(S)-4,5,6,7-Tetrahydro-benzothiazole-2,6-diamine;(S)-(-)-2,6-diamino-4,5,6,7-tetrahydrobenzothiazole;S-(-)-2,6-Diamino-4,5,6,7-tetrahydrobenzothiazole;(6S)-4,5,6,7-Tetrahydro-1,3-benzothiazol-2,6-diamine;2,6-Diamino-4,5,6,7-tetrahydrobenzothiazole, (S)-;J4N3Y41JML;(S)-4,5,6,7-Tetrahydrobenzothiazole-2,6-diamine;MFCD07368003;2,6-Diamino-4,5,6,7-tetrahydrobenzothiazole, (-)-;2,6-benzothiazolediamine, 4,5,6,7-tetrahydro-, (6s)-;UNII-J4N3Y41JML;2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-, (S)-;Pramipexole Intermediates;EC 600-715-3;SCHEMBL306889;( inverted exclamation markA)-2,6-Diamino-4,5,6,7-tetrahydrobenzothiazole;CHEMBL1192854;(-)-(6s)-2,6-diamino-4,5,6,7-tetrahydrobenzothiazole;DTXSID00893656;DRRYZHHKWSHHFT-BYPYZUCNSA-N;Pramipexole dihydrochloride monohydrate specified impurity A [EP];AKOS005258071;AC-1609;CS-W003372;112GI015;DS-10467;D4337;A13055;EN300-208203;(6S)2,6 diamino-4,5,6,7-tetrahydro-benzothiazole;(S)-2,6-diamino-4,5,6,7-tetrahvdro benzothiazole;(s)-2,6-diamino-4,5,6,7-tetrahydro benzothiazole;(6S)-2,6 diamino-4,5,6,7-tetrahydro-benzothiazole;6-(S)-2,6-Diamino-4,5,6,7-tetrahydrobenzothiazole;Q27281199;Z1201624020;(S)-(-)-2,6-Diamino-4,5,6,7-tetrahydrobenzothiazole, 97%;(S)-4,5,6,7-tetrahydro-2,6-benzothiazolediamine, AldrichCPR;PRAMIPEXOLE DIHYDROCHLORIDE MONOHYDRATE IMPURITY A [EP IMPURITY];(S)-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine

Suppliers and Price of (s)-4,5,6,7-Tetrahydrobenzo[d]thiazole-2,6-diamine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(S)-N-DespropylPramipexole
100mg
$ 65.00

TCI Chemical
(S)-(-)-2,6-Diamino-4,5,6,7-tetrahydrobenzothiazole >98.0%(GC)(T)
1g
$ 18.00

TCI Chemical
(S)-(-)-2,6-Diamino-4,5,6,7-tetrahydrobenzothiazole >98.0%(GC)(T)
5g
$ 34.00

SynQuest Laboratories
(S)-(-)-4,5,6,7-Tetrahydrobenzothiazole-2,6-diamine
100 g
$ 234.00

SynQuest Laboratories
(S)-(-)-4,5,6,7-Tetrahydrobenzothiazole-2,6-diamine
25 g
$ 79.00

Sigma-Aldrich
(S)-(?)-2,6-Diamino-4,5,6,7-tetrahydrobenzothiazole 97%
1g
$ 56.10

Sigma-Aldrich
Pramipexole Related Compound A Pharmaceutical Secondary Standard; Certified Reference Material
50mg
$ 482.00

Sigma-Aldrich
Pramipexole Related Compound A United States Pharmacopeia (USP) Reference Standard
15mg
$ 1260.00

Medical Isotopes, Inc.
(-)-(6S)-2,6-Diamino-4,5,6,7-tetrahydrobenzothiazole
50 mg
$ 190.00

Matrix Scientific
(S)-4,5,6,7-Tetrahydrobenzo[d]thiazole-2,6-diamine 95+%
1g
$ 25.00

Total 175 raw suppliers

Chemical Property of (s)-4,5,6,7-Tetrahydrobenzo[d]thiazole-2,6-diamine Edit

Chemical Property:

Appearance/Colour:Pale beige solid
Vapor Pressure:0mmHg at 25°C
Melting Point:222-224 °C
Refractive Index:1.656
Boiling Point:359 °C at 760 mmHg
PKA:9.18±0.20(Predicted)
Flash Point:170.9 °C
PSA：92.31000
Density:1.313 g/cm³
LogP:2.04940
Storage Temp.:-20°C Freezer
Solubility.:DMSO (Slightly), Methanol (Slightly, Heated)
XLogP3:0.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:169.06736854
Heavy Atom Count:11
Complexity:153

Purity/Quality:

99%min ^*data from raw suppliers

(S)-N-DespropylPramipexole ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2=C(CC1N)SC(=N2)N
Isomeric SMILES:C1CC2=C(C[C@H]1N)SC(=N2)N
Uses (S)-Pramipexole intermediate as dopamine autoreceptor agonist. (S)-N-Despropyl Pramipexole is a (S)-Pramipexole (P700745) intermediate as dopamine autoreceptor agonist. (S)-N-Despropyl Pramipexole (Pramipexole EP Impurity A; Pramipexole BP Impurity A; Pramipexole USP Related Compound A) is a (S)-Pramipexole (P700755) intermediate as dopamine autoreceptor agonist.

Technology Process of (s)-4,5,6,7-Tetrahydrobenzo[d]thiazole-2,6-diamine

There total 18 articles about (s)-4,5,6,7-Tetrahydrobenzo[d]thiazole-2,6-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 873431-80-2
(S)-4,5,6,7-tetrahydro-benzothiazole-2,6-diamine tartrate trihydrate

: 106092-09-5,104617-49-4
(S)-4,5,6,7-tetrahydrobenzo[d]thiazol-2,6-diamine

Guidance literature:: (S)-4,5,6,7-tetrahydro-benzothiazole-2,6-diamine tartrate trihydrate; With water; pyrographite; at 80 ℃; for 1h;

With water; potassium hydroxide; sodium hydroxide; at 10 - 20 ℃; for 0.5h; pH=12; Temperature;