asiatic acid benzyl ester

Base Information

• Chemical Name: asiatic acid benzyl ester
• CAS No.: 209901-49-5
• Molecular Formula: C₃₇H₅₄O₅
• Molecular Weight: 578.833
• Mol file: 209901-49-5.mol

Synonyms:asiatic acid benzyl ester

Chemical Property of asiatic acid benzyl ester

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of asiatic acid benzyl ester

There total 2 articles about asiatic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

asiatic acid (464-92-6,89786-83-4,103974-74-9,106327-64-4,114580-55-1,116348-15-3,143839-02-5) + benzyl chloride (100-44-7) → asiatic acid benzyl ester (209901-49-5)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 60 ℃; for 2h; Cooling;

DOI:10.1002/cbdv.200800092

Reference yield: 60.0%

asiatic acid (464-92-6,89786-83-4,103974-74-9,106327-64-4,114580-55-1,116348-15-3,143839-02-5) + benzyl bromide (100-39-0) → asiatic acid benzyl ester (209901-49-5)

Guidance literature:

asiatic acid; With potassium carbonate; In N,N-dimethyl-formamide; for 0.5h;

benzyl bromide; In N,N-dimethyl-formamide; at 20 ℃; for 6h;

DOI:10.3390/molecules24193535

Reference yield: 86.0%

asiatic acid benzyl ester (209901-49-5) + 2,2-dimethoxy-propane (77-76-9) → benzyl 2α-hydroxy-3β,23-(isopropylidenedioxy)urs-12-en-28-oate (1195758-17-8)

Guidance literature:

With toluene-4-sulfonic acid; In N,N-dimethyl-formamide; at 20 ℃; for 7h;

DOI:10.1002/cbdv.200800092

upstream raw materials:

asiatic acid

benzyl chloride

benzyl bromide

Downstream raw materials:

benzyl 2α-hydroxy-3β,23-(isopropylidenedioxy)urs-12-en-28-oate

Refernces

• 1、 Zhang, Liying,Chen, Jun,Gong, Yanchun,Liu, Jun,Zhang, Luyong,Hua, Weiyi,Sun, Hongbin. "Synthesis and biological evaluation of asiatic acid derivatives as inhibitors of glycogen phosphorylases". experimental part. p. 864 - 874. Retrieved 2010/04/23.