Triphenylphosphonium bromide

Base Information

• Chemical Name: Triphenylphosphonium bromide
• CAS No.: 6399-81-1
• Molecular Formula: C18H15P^.HBr
• Molecular Weight: 343.203
• Hs Code.: 29310095
• Mol file: 6399-81-1.mol

Synonyms:Triphenylphosphonium bromide;triphenylphosphine-hbr;PPh3.HBr;(triphenylphosphonium)bromide;Triphenyl phosphonium bromide;triphenyl-phosphonium Bromide;SCHEMBL71504;tri phenyl phosphonium bromide;triphenyl-phospho-nium bromide;triphenyl phosphine hydrobromide;AKOS025311067;W-104866

Chemical Property of Triphenylphosphonium bromide

Chemical Property:

• Appearance/Colour: white to light beige crystalline powder or chunks
• Melting Point: 196 °C (dec.)(lit.)
• Boiling Point: 360 °C at 760 mmHg
• Flash Point: 181.7 °C
• PSA: 13.59000
• LogP: 4.40290
• Storage Temp.: -20°C
• Solubility.: DMSO (Slightly), Methanol (Slightly)
• Water Solubility.: Soluble in water.
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 342.01730
• Heavy Atom Count: 20
• Complexity: 202

Purity/Quality:

99% ^*data from raw suppliers

Triphenylphosphine hydrobromide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C,Xi
• Statements: 22-34-36/37/38
• Safety Statements: 26-36/37/39-45-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)[PH+](C2=CC=CC=C2)C3=CC=CC=C3.[Br-]
• Uses: Triphenylphosphine hydrobromide is the hydrobromide salt of Triphenylphosphine, used in the preparation of uridine derivatives as substrate donor analogs of UDP-sugars for glycosyltransferases. Also used in the preparation of tensioactive and antibacterial deoxyglycoside compounds via catalysis. Triphenylphosphine hydrobromide is used as mild source of anhydrous HBr; catalyst for formation of THP ethers from tertiary alcohols; preparation of phosphonium salts.

Technology Process of Triphenylphosphonium bromide

There total 7 articles about Triphenylphosphonium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

triphenylphosphine (603-35-0) → triphenylphosphine hydrobromide (6399-81-1)

Guidance literature:

With hydrogen bromide; toluene; In water; at 70 ℃;

Reference yield:

t-butyl bromide (507-19-7) + triphenylphosphine (603-35-0) → triphenylphosphine hydrobromide (6399-81-1)

Guidance literature:

With tetrabutylammomium bromide; for 3h; Heating;

DOI:10.1055/s-1994-25506

Reference yield:

(1-methylethyl)triphenylphosphonium bromide (3968-92-1) → triphenylphosphine hydrobromide (6399-81-1)

Guidance literature:

at 275 ℃; for 0.333333h;

DOI:10.1246/bcsj.80.1785

upstream raw materials:

t-butyl bromide

triphenylphosphine

(1-methylethyl)triphenylphosphonium bromide

(indan-1-yl)triphenylphosphonium bromide

Downstream raw materials:

[1,1'-(butane-1,4-diyl)bis(triphenylphosphonium)] dibromide

(3-methylbut-2-enyl)triphenylphosphonium bromide

n-propyltriphenylphosphonium bromide

((E)-3-methyl-hex-2-enyl)-triphenyl-phosphonium; bromide

Refernces

• 1、 Fayzullin, Robert R.,Grigor'eva, Leysan R.,Khasiyatullina, Nadezhda R.,Mironov, Vladimir F.,Nemtarev, Andrey V.,Shemakhina, Mariya E.. "Reaction of R-pulegone with P–H phosphonium salts". . p. 700 - 702. Retrieved 2021/01/12.
• 2、 -. "Production of cyclic carbonate". Paragraph 0134. . Retrieved 2017/11/08.