4-Bromo-3,5-difluoroanisole

Base Information

• Chemical Name: 4-Bromo-3,5-difluoroanisole
• CAS No.: 202865-61-0
• Molecular Formula: C₇H₅BrF₂O
• Molecular Weight: 223.017
• Hs Code.: 29093090
• European Community (EC) Number: 679-553-0
• DSSTox Substance ID: DTXSID90369315
• Nikkaji Number: J3.151.454A
• Wikidata: Q72454269
• Mol file: 202865-61-0.mol

Synonyms:4-Bromo-3,5-difluoroanisole;202865-61-0;2-Bromo-1,3-difluoro-5-methoxybenzene;3,5-Difluoro-4-Bromoanisole;Benzene, 2-bromo-1,3-difluoro-5-methoxy-;2-bromo-1,3-difluoro-5-methoxy-benzene;SCHEMBL1552502;DTXSID90369315;GEJMNTXYFBBTFH-UHFFFAOYSA-N;2,6-difluoro-4-methoxybromobenzene;2,6-difluoro-4-methoxy-bromobenzene;BBL103668;MFCD00143268;STL557478;AKOS009158713;AC-1139;CS-W010462;AS-15680;A4413;AM20050184;B3392;FT-0617806;EN300-1915586;J-013183

Chemical Property of 4-Bromo-3,5-difluoroanisole

Chemical Property:

• Appearance/Colour: clear slightly yellow liquid or white crystalline
• Vapor Pressure: 0.005mmHg at 25°C
• Melting Point: 26-30 °C
• Refractive Index: 1.5225-1.5245
• Boiling Point: 176.5 °C at 760 mmHg
• Flash Point: 72.6 °C
• PSA: 9.23000
• Density: 1.615 g/cm³
• LogP: 2.73590
• Storage Temp.: Sealed in dry,Room Temperature
• Water Solubility.: Insoluble in water.
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 221.94918
• Heavy Atom Count: 11
• Complexity: 122

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Bromo-3- ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi, T
• Hazard Codes: Xi,T
• Statements: 36/37/38-36/38
• Safety Statements: 37/39-26-37

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC(=C(C(=C1)F)Br)F
• Uses: It is used to prepare difluorophenacyl analogs as inhibitors of cyclin-dependent kinases. It is also used to synthesize aminopyridine N-oxides for selective inhibition of p38 MAP kinase. 4-Bromo-3,5-difluoroanisole is used to prepare difluorophenacyl analogs as inhibitors of cyclin-dependent kinases. It is also used to synthesize aminopyridine N-oxides for selective inhibition of p38 MAP kinase.