Enoximone

Base Information Edit

Chemical Name:Enoximone
CAS No.:77671-31-9
Molecular Formula:C12H12 N2 O2 S
Molecular Weight:248.305
Hs Code.:2933290090
UNII:C7Z4ITI7L7
DSSTox Substance ID:DTXSID8045147
Nikkaji Number:J22.780C
Wikipedia:Enoximone
Wikidata:Q5379471
NCI Thesaurus Code:C87375
Pharos Ligand ID:BXFCZ3HH3DUL
Metabolomics Workbench ID:43639
ChEMBL ID:CHEMBL249856
Mol file:77671-31-9.mol

Synonyms:Enoximone;Fenoximone;MDL 17,043;MDL 17043;MDL 19,438;MDL 19438;MDL-17,043;MDL-17043;MDL-19,438;MDL17,043;MDL17043;MDL19,438;Perfan

Suppliers and Price of Enoximone

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Enoximone
10mg
$ 423.00

Tocris
Enoximone ≥99%(HPLC)
50
$ 711.00

Tocris
Enoximone ≥99%(HPLC)
10
$ 169.00

Sigma-Aldrich
Enoximone solid
50mg
$ 854.00

Sigma-Aldrich
Enoximone solid
10mg
$ 225.00

Medical Isotopes, Inc.
Enoximone
5 mg
$ 990.00

Chemtos
EnoximoneSulfoxide
25 mg
$ 1190.00

ChemScene
Enoximone 98.05%
25mg
$ 320.00

ChemScene
Enoximone 98.05%
10mg
$ 160.00

ChemScene
Enoximone 98.05%
100mg
$ 980.00

Total 51 raw suppliers

Chemical Property of Enoximone Edit

Chemical Property:

Melting Point:255-258 ºC
PKA:10.37±0.70(Predicted)
PSA：91.02000
Density:1.33
LogP:1.96430
Storage Temp.:Store at +4°C
Solubility.:DMSO: 28 mg/mL, soluble
XLogP3:1.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:248.06194880
Heavy Atom Count:17
Complexity:371

Purity/Quality:

98%,99%, ^*data from raw suppliers

Enoximone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(NC(=O)N1)C(=O)C2=CC=C(C=C2)SC
Recent ClinicalTrials:The Effects of Enoximone in Acute Exacerbation COPD
Recent EU Clinical Trials:The effects of enoximone in acute exacerbation COPD: a pilot study
Description Enoximone is a phosphodiesterase inhibitor indicated for selective use as a cardiostimulant in heart transplant patient maintenance. It is currently being investigated for other indications including acute congestive heart failure.
Uses Enoximone is a phosphodiesterase inhibitor used in the treatment of congestive heart failure and is selective to phosphodiesterase 3. Potent PDE-3 inhibitor.

Technology Process of Enoximone

There total 10 articles about Enoximone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%