N,N-Bis(3-aminopropyl)methylamine

Base Information

• Chemical Name: N,N-Bis(3-aminopropyl)methylamine
• CAS No.: 105-83-9
• Deprecated CAS: 113277-73-9,92213-62-2,92213-62-2
• Molecular Formula: C7H19N3
• Molecular Weight: 145.248
• Hs Code.: 2921290000
• European Community (EC) Number: 203-336-8,234-292-8
• NSC Number: 8173
• UNII: 62ZM34D74O
• DSSTox Substance ID: DTXSID1044510
• Nikkaji Number: J1.184C
• Wikidata: Q27263529
• ChEMBL ID: CHEMBL283720
• Mol file: 105-83-9.mol

Synonyms:3,3'-diamino-N-methyldipropylamine;DAMDPA compound

Chemical Property of N,N-Bis(3-aminopropyl)methylamine

Chemical Property:

• Vapor Pressure: 6 mm Hg ( 110 °C)
• Melting Point: -30--28 °C
• Refractive Index: n20/D 1.4725(lit.)
• Boiling Point: 252.9 °C at 760 mmHg
• PKA: pK1:6.32(＋3);pK2:9.19(＋2);pK3:10.33(＋1) (30°C)
• Flash Point: 102.8 °C
• PSA: 55.28000
• Density: 0.915 g/cm³
• LogP: 1.01640
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility.: Completely miscible in water
• Water Solubility.: 1000g/L at 20℃
• XLogP3: -0.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 6
• Exact Mass: 145.157897619
• Heavy Atom Count: 10
• Complexity: 57.9

Purity/Quality:

99.9% ^*data from raw suppliers

N,N-Bis(3-aminopropyl)methylamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T
• Hazard Codes: T
• Statements: 22-23/24-34
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(CCCN)CCCN
• Uses: 3,3′-Diamino-N-methyldipropylamine was used in the synthesis of:new bischromone derivatives, potential anticancer drugspolyamine derivatives containing dimeric quinolone, cinnoline and phthalimide moieties3-(2,4-dinitroanilino)-3′-amino-N-methyldipropylamine

Technology Process of N,N-Bis(3-aminopropyl)methylamine

There total 3 articles about N,N-Bis(3-aminopropyl)methylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

Bis(2-cyanoethyl)methylamine (1555-58-4) → 3,3'-Diamino-N-methyldipropylamine (105-83-9)

Guidance literature:

With hydrogen; sodium hydroxide; In ethanol; at 90 ℃; under 15001.5 Torr; Autoclave; Green chemistry;

DOI:10.3184/174751916X14665047142757

Reference yield:

Bis(2-cyanoethyl)methylamine (1555-58-4) → 1-methyl-[1,5]diazocane (4318-36-9) + 3,3'-Diamino-N-methyldipropylamine (105-83-9)

Guidance literature:

With ammonia; nickel; at 90 - 100 ℃; under 73550.8 Torr; Hydrogenation;

Reference yield:

→ 3,3'-Diamino-N-methyldipropylamine (105-83-9)

Guidance literature:

upstream raw materials:

Bis(2-cyanoethyl)methylamine

Downstream raw materials:

N'-[3-(dimethylamino)propyl]-N,N,N'-trimethylpropane-1,3-diamine

(4,6-(MeO)2-SMDPTH₂)

N-(4,5-dichloro-2-nitro-phenyl)-N'-[3-(4,5-dichloro-2-nitro-phenylamino)-propyl]-N'-methyl-propane-1,3-diamine

Refernces

• 1、 -. "Silicone containing bis-thioether aromatic amines". . . Retrieved 2008/06/13.