alpha-[1-(T-Butylamino)ethyl]-2,5-dimethoxybenzyl alcohol hydrochloride

Base Information

• Chemical Name: alpha-[1-(T-Butylamino)ethyl]-2,5-dimethoxybenzyl alcohol hydrochloride
• CAS No.: 5696-15-1
• Molecular Formula: C₁₅H₂₅NO₃*ClH
• Molecular Weight: 303.829
• UNII: 2O68ZJ8BLQ
• Wikidata: Q27255200
• NCI Thesaurus Code: C64184
• ChEMBL ID: CHEMBL1884451
• Mol file: 5696-15-1.mol

Synonyms:2O68ZJ8BLQ;MLS000028672;SMR000058900;Butoxamine HCl;Butoxamine hydrochloride [USAN];BW 64-9;Butaxamine hydrochloride;UNII-2O68ZJ8BLQ;EINECS 227-169-5;BW 64 9;BW-64-9;ALPHA-[1-(T-BUTYLAMINO)ETHYL]-2,5-DIMETHOXYBENZYL ALCOHOL HYDROCHLORIDE;BW- 64-9;B. W. 64-9;Opera_ID_1665;MLS001074128;CHEMBL1884451;Benzenemethanol, alpha-(1-((1,1-dimethylethyl)amino)ethyl)-2,5-dimethoxy-, hydrochloride;(1R,2S)-2-(tert-butylamino)-1-(2,5-dimethoxyphenyl)propan-1-ol hydrochloride;Q27255200;Benzyl alcohol, alpha-(1-(tert-butylamino)ethyl)-2,5-dimethoxy-, hydrochloride;BENZENEMETHANOL, .ALPHA.-(1-((1,1-DIMETHYLETHYL)AMINO)ETHYL)-2,5-DIMETHOXY-, (R*,S*)-, HYDROCHLORIDE, (+/-)-;Benzenemethanol, alpha-(1-((1,1-dimethylethyl)amino)ethyl)-2,5-dimethoxy-, (R*,S*)-, hydrochloride, (+-)-

Chemical Property of alpha-[1-(T-Butylamino)ethyl]-2,5-dimethoxybenzyl alcohol hydrochloride

Chemical Property:

• Vapor Pressure: 8.18E-07mmHg at 25°C
• Boiling Point: 391°C at 760 mmHg
• Flash Point: 190.3°C
• PSA: 50.72000
• LogP: 3.70670
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 6
• Exact Mass: 303.1601214
• Heavy Atom Count: 20
• Complexity: 265

Purity/Quality:

95-99% ^*data from raw suppliers

Butoxamine hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22-36
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C(C1=C(C=CC(=C1)OC)OC)O)NC(C)(C)C.Cl
• Isomeric SMILES: C[C@@H]([C@@H](C1=C(C=CC(=C1)OC)OC)O)NC(C)(C)C.Cl
• Uses: Butoxamine Hydrochloride is a beta-2 selective beta blocker. β2-adrenergic receptor(AR) antagonist; Antiarrhythmic
• Therapeutic Function: Oral hypoglycemic, Antihyperlipidemic

Technology Process of alpha-[1-(T-Butylamino)ethyl]-2,5-dimethoxybenzyl alcohol hydrochloride

There total 2 articles about alpha-[1-(T-Butylamino)ethyl]-2,5-dimethoxybenzyl alcohol hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ Butoxamine hydrochloride (1937-88-8,5696-15-1,21062-63-5,21062-64-6,21062-65-7,21062-66-8)

Guidance literature:

2,5-Dimethoxy-α-tert.-butylamino-propiophenonhydrochlorid, NaBH4;

DOI:10.1021/jm00310a030

Reference yield:

→ N-tert.-Butyl-methoxaminhydrochlorid (1937-88-8,5696-15-1,21062-63-5,21062-64-6,21062-65-7,21062-66-8)

Guidance literature:

2,5-Dimethoxy-α-tert.-butylamino-propiophenonhydrochlorid, H2 (PtO2);

DOI:10.1021/jm00310a030

Refernces