Dimefox

Base Information

• Chemical Name: Dimefox
• CAS No.: 115-26-4
• Molecular Formula: C4H12 F N2 O P
• Molecular Weight: 154.124
• European Community (EC) Number: 204-076-8
• UN Number: 3018
• UNII: N8RU9F1IQD
• DSSTox Substance ID: DTXSID8041870
• Nikkaji Number: J5.264G
• Wikipedia: Dimefox
• Wikidata: Q424882
• Mol file: 115-26-4.mol

Synonyms:bis(dimethylamido)phosphoryl fluoride;dimefox

Chemical Property of Dimefox

Chemical Property:

• Vapor Pressure: 2.83mmHg at 25°C
• Refractive Index: 1.4267 (589.3 nm 20℃)
• Boiling Point: 156.9°Cat760mmHg
• PKA: -0.24±0.70(Predicted)
• Flash Point: 48.7°C
• Density: 1.111g/cm³
• Storage Temp.: +4°C
• XLogP3: -0.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 154.06712817
• Heavy Atom Count: 9
• Complexity: 125
• Transport DOT Label: Poison

Purity/Quality:

TetramethylphosphorodiamidicFluoride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Cholinesterase inhibitor, use may be restricted. TLV: 2.5 mg(F)/m³.
• Hazard Codes: T+
• Statements: 27/28
• Safety Statements: 23-28-36/37-38-45

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Pesticides -> Organophosphate Insecticides
• Canonical SMILES: CN(C)P(=O)(N(C)C)F
• Uses: Insecticide; acaricide.

Technology Process of Dimefox

There total 11 articles about Dimefox which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

N,N,N',N'-Tetramethylphosphorodiamidic chloride (1605-65-8) → dimefox (115-26-4)

Guidance literature:

With Amberlyst(R) A-26 resin; In tetrahydrofuran; at 20 ℃; for 2.5h;

DOI:10.1016/j.tetlet.2005.02.026

Reference yield: 77.0%

N,N,N',N'-Tetramethylphosphorodiamidic chloride (1605-65-8) → N,N,N,N,N,N-hexamethylphosphoric triamide (680-31-9) + dimefox (115-26-4) + N,N-dimethylphosphoramidic difluoride (354-43-8)

Guidance literature:

With sodium hexaflorophosphate; In various solvent(s); at 200 ℃; for 0.25h;

DOI:10.1039/a908932b

Reference yield: 20.0%

Hexamethylphosphorous triamide (1608-26-0) → dimefox (115-26-4)

Guidance literature:

With N,N,N,N-tetraethylammonium tetrafluoroborate; current density 3.3-5.0 mA/cm²;

upstream raw materials:

schradan

N,N,N',N'-Tetramethylphosphorodiamidic chloride

N,N-dimethylphosphoramidic difluoride

dimethyl amine

Downstream raw materials:

phosphoryl dichloride fluoride

N,N-dimethylammonium chloride

Refernces

• 1、 Robinson,E.A.,Lavery,D.S.. "-". . p. 1099 - 1101. Retrieved 1972.
• 2、 Ramirez,F. et al.. "-". . p. 3651 - 3656. Retrieved 1966.
• 3、 Zhang, Cheng-Pan,Chen, Qing-Yun,Xiao, Ji-Chang. "Reactions of HMPA with hexafluorobenzene, pentafluorochlorobenzene and pentafluorophenol". . p. 424 - 428. Retrieved 2008/12/22.