1-(3-Methylphenyl)piperazine

Base Information Edit

Chemical Name:1-(3-Methylphenyl)piperazine
CAS No.:41186-03-2
Molecular Formula:C11H16N2
Molecular Weight:176.261
Hs Code.:29335990
European Community (EC) Number:255-251-0
NSC Number:184825
UNII:FYS4L9BW6G
DSSTox Substance ID:DTXSID30194108
Nikkaji Number:J231.928D
Wikidata:Q72495120
ChEMBL ID:CHEMBL165175
Mol file:41186-03-2.mol

Synonyms:1-(3-Methylphenyl)piperazine;41186-03-2;1-(m-Tolyl)piperazine;1-m-tolylpiperazine;1-(3-Methylphenyl)-piperazine;Piperazine, 1-(3-methylphenyl)-;1-m-Tolyl-piperazine;MFCD00040734;FYS4L9BW6G;CHEMBL165175;EINECS 255-251-0;NSC-184825;NSC-150848;4-m-tolylpiperazine;1-m-tolyl-piperzine;ACOVENOSIDEA;4-m-tolyl-piperazine;3-methylphenylpiperazine;3-methyl phenylpiperazine;Maybridge4_000089;UNII-FYS4L9BW6G;Cc1cccc(c1)N2CCNCC2;NCIOpen2_003566;SCHEMBL81365;1-(m-Methylphenyl)piperazine;4-(3-methylphenyl)piperazine;N-(3-TOLYL)PIPERAZINE;1-(3-methyl phenyl)piperazine;1-(3-methylphenyl) piperazine;JIWHIRLNKIUYSM-UHFFFAOYSA-;DTXSID30194108;BDBM50001904;NSC184825;STK500994;AKOS000101165;FS-1235;NSC 184825;IDI1_030671;BP-10761;A6836;FT-0605635;T2260;EN300-23498;1-(3-Methylphenyl)piperazine, >=97.5% (HPLC);J-503165;F2190-0518;Z150862988

Suppliers and Price of 1-(3-Methylphenyl)piperazine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-(3-Methylphenyl)piperazine
5g
$ 150.00

TCI Chemical
1-(m-Tolyl)piperazine >95.0%(GC)
25g
$ 69.00

TCI Chemical
1-(m-Tolyl)piperazine >95.0%(GC)
5g
$ 27.00

SynQuest Laboratories
1-(3-Methylphenyl)piperazine 98%
5 g
$ 75.00

SynQuest Laboratories
1-(3-Methylphenyl)piperazine 98%
1 g
$ 50.00

Matrix Scientific
1-(3-Methylphenyl)piperazine
500mg
$ 95.00

CHESS?
1-(3-Methylphenyl)-piperazine 98
10 g
$ 6020.00

CHESS?
1-(3-Methylphenyl)-piperazine 98
2 g
$ 2110.00

Chem-Impex
1-(m-Tolyl)piperazine,≥95%(GC)Hazmat ≥95%(GC)
25G
$ 77.42

American Custom Chemicals Corporation
1-(3-METHYLPHENYL)PIPERAZINE 95.00%
5G
$ 1005.43

Total 52 raw suppliers

Chemical Property of 1-(3-Methylphenyl)piperazine Edit

Chemical Property:

Appearance/Colour:clear colorless to yellow viscous liquid
Vapor Pressure:0.000299mmHg at 25°C
Melting Point:125-128 °C
Refractive Index:1.5755-1.5785
Boiling Point:321.4 °C at 760 mmHg
PKA:9.05±0.10(Predicted)
Flash Point:154 °C
PSA：15.27000
Density:1.012 g/cm³
LogP:1.79840
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:176.131348519
Heavy Atom Count:13
Complexity:152

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-(3-Methylphenyl)piperazine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 37/39-26-36/37/39

MSDS Files:

Useful:

Canonical SMILES:CC1=CC(=CC=C1)N2CCNCC2
Uses 1-(3-Methylphenyl)piperazine is used in preparation of (2,5-Dioxopyrrolidin-L-yl)(phenyl)acetamide derivatives useful in treatment of neurological disorders.

Technology Process of 1-(3-Methylphenyl)piperazine

There total 9 articles about 1-(3-Methylphenyl)piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 41186-03-2
1-(3-Methylphenyl)piperazine

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 2h;

Reference yield: 92.0%

: 13078-13-2,178928-62-6
1-(m-tolyl)piperazine hydrochloride

: 41186-03-2
1-(3-Methylphenyl)piperazine

Guidance literature:: With sodium hydroxide; In water; at 20 ℃; for 0.5h; pH=11 - 12;
DOI:10.1111/cbdd.13324

Reference yield: 82.0%

: 110-85-0
piperazine

: 108-41-8
1-chloro-3-methylbenzene

: 41186-03-2
1-(3-Methylphenyl)piperazine

: 3477-33-6
1,4-bis(3-methylphenyl)piperazine

Guidance literature:: piperazine; With [2,2]bipyridinyl; nickel diacetate; sodium hydride; tert-Amyl alcohol; In tetrahydrofuran; at 65 ℃; for 2h;

1-chloro-3-methylbenzene; With styrene; In tetrahydrofuran; at 65 ℃; for 6h;
DOI:10.1016/S0040-4020(02)00750-0