Pyronin Y

Base Information

• Chemical Name: Pyronin Y
• CAS No.: 92-32-0
• Deprecated CAS: 115624-92-5,167382-93-6,20195-95-3,61260-70-6,167382-93-6,20195-95-3,61260-70-6
• Molecular Formula: C17H19 N2 O . Cl
• Molecular Weight: 302.804
• Hs Code.: 32041300
• European Community (EC) Number: 202-147-8
• NSC Number: 10454
• UNII: W659G165T1
• DSSTox Substance ID: DTXSID8059051
• Wikidata: Q2120020
• Metabolomics Workbench ID: 67537
• ChEMBL ID: CHEMBL1486690
• Mol file: 92-32-0.mol

Synonyms:Pyronin Y;Pyronine;Pyronine G

Chemical Property of Pyronin Y

Chemical Property:

• Appearance/Colour: dark green to brown crystals.
• Melting Point: 250-260 °C(lit.)
• PSA: 19.39000
• LogP: -0.36060
• Storage Temp.: Store at RT.
• Solubility.: Soluble in water; sparingly soluble in ethanol, ethylene glycol,
• Water Solubility.: Soluble in water. Also soluble in methyl cellosolve (9 mg/mL) and ethanol (3 mg/mL).
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 302.1185909
• Heavy Atom Count: 21
• Complexity: 480

Purity/Quality:

98%,99%, ^*data from raw suppliers

PyronineY,TechnicalGrade ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn,Xi
• Statements: 68-36/37/38
• Safety Statements: 22-24/25-36-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Dyes -> Acridine Dyes
• Canonical SMILES: CN(C)C1=CC2=C(C=C1)C=C3C=CC(=[N+](C)C)C=C3O2.[Cl-]
• Uses: Bacterial and biological stain. Pyronin Y is a cationic dye that intercalates RNA and is visible as a red band during electrophoresis. It has also been shown to accumulate in mitochondria of viable cells. In conjuction with Methyl Green or Nancy-520, Pyronin Y can be used as a fluorescent differential stain of nucleic acids in paraffin tissue sections. Pyronin Y has been used: in the purification of quiescent and cycling hematopoietic stem cells and staining of bone marrow cells (HSCs)as a component of the polychlorinated biphenyls (PCBS) solution for staining mammary gland side population cells (MG-SPs)staining of CD34+ cells

Technology Process of Pyronin Y

There total 3 articles about Pyronin Y which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

βCD.PY+ (116060-89-0) → pyronin Y (92-32-0) + β‐cyclodextrin (7585-39-9)

Guidance literature:

at 25.04 ℃; Solvent; Equilibrium constant; aq. buffer;

DOI:10.1071/CH09467

Reference yield:

66βCD2succ.PY+ → pyronin Y (92-32-0) + di-N,N'-(mono-6'-deoxy-6'-amidosuccinyl-β-cyclomaltoheptaosyl)succinamide (130912-23-1)

Guidance literature:

at 25.04 ℃; Solvent; Equilibrium constant; aq. buffer;

DOI:10.1071/CH09467

Reference yield:

33βCD2succ.PY+ → pyronin Y (92-32-0) + N,N'-bisbutane-1,4-diamide

Guidance literature:

at 25.04 ℃; Solvent; Equilibrium constant; aq. buffer;

DOI:10.1071/CH09467

upstream raw materials:

βCD.PY+

Downstream raw materials:

N₃,N₃,N₆,N₆-tetramethyl-9H-xanthene-3,6-diamine

N,N,N’,N’-tetramethylrhodamine xanthone

Refernces