Ketone, 3-indolyl piperidinomethyl

Base Information

• Chemical Name: Ketone, 3-indolyl piperidinomethyl
• CAS No.: 30256-73-6
• Molecular Formula: C₁₅H₁₈N₂O
• Molecular Weight: 242.321
• DSSTox Substance ID: DTXSID50184349
• Nikkaji Number: J62.516G
• Wikidata: Q83055280
• ChEMBL ID: CHEMBL1353722
• Mol file: 30256-73-6.mol

Synonyms:BRN 0479623;KETONE, 3-INDOLYL PIPERIDINOMETHYL;Indolyl-3-piperidinomethyl ketone;30256-73-6;1-(1H-Indol-3-yl)-2-piperidin-1-yl-ethanone;3-(N-piperidyl)acetylindole;MLS001210533;SCHEMBL1413908;CHEMBL1353722;DTXSID50184349;HMS2837K09;HMS3428H18;STK325065;AKOS000562486;CCG-110428;1H-Indol-3-yl(piperidinomethyl) ketone;NCGC00245116-01;LS-87257;SMR000513985;1-(1H-indol-3-yl)-2-(piperidin-1-yl)ethanone;SR-01000478934;SR-01000478934-1

Chemical Property of Ketone, 3-indolyl piperidinomethyl

Chemical Property:

• Vapor Pressure: 8.53E-08mmHg at 25°C
• Boiling Point: 435.8°C at 760 mmHg
• Flash Point: 217.3°C
• Density: 1.17g/cm³
• XLogP3: 3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 242.141913202
• Heavy Atom Count: 18
• Complexity: 299

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCN(CC1)CC(=O)C2=CNC3=CC=CC=C32

Technology Process of Ketone, 3-indolyl piperidinomethyl

There total 2 articles about Ketone, 3-indolyl piperidinomethyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

piperidine (110-89-4) + 3-chloroacetylindole (28755-03-5) → indol-3-yl piperidinomethyl ketone (30256-73-6)

Guidance literature:

In N,N-dimethyl-formamide; at 80 ℃; for 4.5h;

Reference yield:

→ indol-3-yl piperidinomethyl ketone (30256-73-6)

Guidance literature:

3-Chloracetyl-indol, Piperidin;

DOI:10.1007/BF00763238

upstream raw materials:

piperidine

3-chloroacetylindole

Refernces