trifluoperazine sulfoxide

Base Information

• Chemical Name: trifluoperazine sulfoxide
• CAS No.: 1549-88-8
• Molecular Formula: C21H24 F3 N3 O S
• Molecular Weight: 423.502
• Mol file: 1549-88-8.mol

Synonyms:Phenothiazine,10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-, 5-oxide(6CI,7CI,8CI); Trifluoperazine S-oxide; Trifluoperazine sulfoxide;Trifluoperazine sulphoxide; Trifluoroperazine sulfoxide; Triphthazine sulfoxide

Chemical Property of trifluoperazine sulfoxide

Chemical Property:

• Vapor Pressure: 2.84E-12mmHg at 25°C
• Boiling Point: 553°Cat760mmHg
• Flash Point: 288.2°C
• PSA: 46.00000
• Density: 1.39g/cm³
• LogP: 4.76760

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Triphthazine Sulfoxide is used for the decomposition of sulfoxide metabolites of phenothiazine antipsychotics during gas chromatographic analysis.

Technology Process of trifluoperazine sulfoxide

There total 7 articles about trifluoperazine sulfoxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

trifluoperazine dihydrochloride (440-17-5) → trifluoroperazine sulfoxide (1549-88-8)

Guidance literature:

With hydrogenchloride; oxygen; cis-nitrous acid; In water; acetonitrile; at -20 ℃;

Reference yield:

C21H24F3N3S(1+) → Trifluoperazine (117-89-5) + trifluoroperazine sulfoxide (1549-88-8)

Guidance literature:

With water; In sulfuric acid; at 24.84 ℃; Concentration; pH-value; Kinetics;

DOI:10.1007/s11243-011-9531-x

Reference yield:

Trifluoperazine (117-89-5) → trifluoroperazine sulfoxide (1549-88-8)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium pyrophosphate; manganese(III) triacetate dihydrate; phosphoric acid / water / 14.84 - 34.84 °C / pH 1.4 - 4 / aq. phosphate buffer

2: sodium pyrophosphate; manganese(III) triacetate dihydrate; phosphoric acid; water / 24.84 °C / pH 1.4 / aq. phosphate buffer

With sodium pyrophosphate; manganese(III) triacetate dihydrate; phosphoric acid; water; In water;

DOI:10.1007/s11243-011-9531-x

upstream raw materials:

trifluoperazine dihydrochloride

Trifluoperazine

Refernces

• 1、 Huang,Bhansali. "-". . p. 1511,1512. Retrieved 1968.
• 2、 Upadhyay, Kanchan,Asthana, Anupama,Tamrakar, Raunak Kumar. "Sensitive spectrophotometric method for determination of some phenothiazine drugs". . p. 7481 - 7495. Retrieved 2015/02/19.