Bopindolol

Base Information

• Chemical Name: Bopindolol
• CAS No.: 62658-63-3
• Deprecated CAS: 69010-88-4
• Molecular Formula: C23H28N2O3
• Molecular Weight: 380.48
• Hs Code.: 2933990090
• UNII: KT304VZO57
• DSSTox Substance ID: DTXSID6022684
• Nikkaji Number: J245.015A
• Wikipedia: Bopindolol
• Wikidata: Q834660
• NCI Thesaurus Code: C169813
• Pharos Ligand ID: Y1JBKGG6DRDS
• Metabolomics Workbench ID: 43723
• ChEMBL ID: CHEMBL357995
• Mol file: 62658-63-3.mol

Synonyms:1-(tert-butylamino)-3-((2-methylindo)-4-yl)-2-propanol benzoate;bopindolol;bopindolol, (+-)-isomer;LT 31-200

Chemical Property of Bopindolol

Chemical Property:

• Vapor Pressure: 1.92E-12mmHg at 25°C
• Refractive Index: 1.592
• Boiling Point: 557 °C at 760 mmHg
• PKA: 17.59±0.30(Predicted)
• Flash Point: 290.7 °C
• PSA: 63.35000
• Density: 1.143 g/cm³
• LogP: 4.85970
• Storage Temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
• Solubility.: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
• XLogP3: 4.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 9
• Exact Mass: 380.20999276
• Heavy Atom Count: 28
• Complexity: 499

Purity/Quality:

98%Min ^*data from raw suppliers

racBopindolol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC2=C(N1)C=CC=C2OCC(CNC(C)(C)C)OC(=O)C3=CC=CC=C3
• Description: Bopindolol is a potent, long-acting, non-selective β-adrenergic blocker related to pindolol and useful in the treatment of hypertension. Unlike many other agents of this type, it appears to have negligible effects on serum lipoproteins.
• Uses: Bopindolol is an ester prodrug of Pindolol (P468000). Bopindolol is a long acting β-adrenoceptor blocking agent. Bopindolol displays antispasmogenic activity mediated by α1-adrenoceptors and 5-HT2 receptors.
• Therapeutic Function: Beta-adrenergic blocker