Tetrabutylammoniumperiodate

Base Information

• Chemical Name: Tetrabutylammoniumperiodate
• CAS No.: 53-59-8
• Deprecated CAS: 10213-33-9,162195-92-8,25158-33-2,2727158-75-8,27678-67-7
• Molecular Formula: C21H28 N7 O17 P3
• Molecular Weight: 743.411
• Hs Code.: 2924199090
• European Community (EC) Number: 200-178-1
• Wikipedia: Nicotinamide_adenine_dinucleotide_phosphate
• Mol file: 53-59-8.mol

Synonyms:53-59-8;beta-Nicotinamide adenine dinucleotide phosphate hydrate;TETRABUTYLAMMONIUMPERIODATE

Chemical Property of Tetrabutylammoniumperiodate

Chemical Property:

• Boiling Point: °Cat760mmHg
• PKA: pKa1 3.9; pKa2 6.1(at 25℃)
• Flash Point: °C
• PSA: 397.05000
• Density: g/cm³
• LogP: -1.17920
• Storage Temp.: −20°C
• Solubility.: H2O: 50 mg/mL, clear, slightly yellow
• Hydrogen Bond Donor Count: 9
• Hydrogen Bond Acceptor Count: 22
• Rotatable Bond Count: 13
• Exact Mass: 761.08601813
• Heavy Atom Count: 49
• Complexity: 1290

Purity/Quality:

99%min ^*data from raw suppliers

b-Nicotinamide adenine dinucleotide phosphate hydrate ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)([O-])OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)OP(=O)(O)O)O)O)O)C(=O)N.O
• Isomeric SMILES: C1=CC(=C[N+](=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)([O-])OP(=O)(O)OC[C@@H]3[C@H]([C@H]([C@@H](O3)N4C=NC5=C(N=CN=C54)N)OP(=O)(O)O)O)O)O)C(=O)N.O
• Description: Triphosphopyridine nucleotide is a coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. Triphosphopyridine nucleotide serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH).
• Uses: β-Nicotinamide adenine dinucleotide phosphate hydrate is suitable for use in:the measurement of Glucose-6-phosphate dehydrogenase activitythe Cytochrome P450 3A4 assay as a part of NADPH-regenerating systemthe Cytochrome P450 2D6 assay as a part of NADPH-regenerating systemthe determination of Glucose-6-phosphate content
• Biological Functions: Triphosphopyridine nucleotide (NADP) serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH).

Technology Process of Tetrabutylammoniumperiodate

There total 14 articles about Tetrabutylammoniumperiodate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

nicotinamide adenine dinucleotide (76961-04-1) → C21H26N7O17P3(2-) (53-59-8)

Guidance literature:

With 2,3-dimercaptopropanol; acetyl diammonium phosphate; NAD kinase; potassium acetate; ATP; magnesium chloride; for 384h; Ambient temperature; pH: 6.8 -7.2;

DOI:10.1021/ja00313a045

Reference yield:

NADPH (53-57-6) → NADP (53-59-8)

Guidance literature:

With hydrogenchloride; NfrA₁ enzyme; nitrofurazone; 2-amino-2-hydroxymethyl-1,3-propanediol; In water; at 23 ℃; pH=7.0; Further Variations:; Reagents; Enzyme kinetics;

DOI:10.1271/bbb.62.1978

Reference yield:

ATP (56-65-5,896506-78-8) → NADP (53-59-8)

Guidance literature:

With NAD⁺-kinase; Enzymatische Bildung;

upstream raw materials:

NADPH

ATP

dicyclohexyl-carbodiimide

adenosine 3',5'-diphosphate

Downstream raw materials:

pNAD

2-keto-glutaramic acid

NADPH

methyl 3-pyridinecarboxylate

Refernces

• 1、 Medvedev,Tyurin,Rozhkova,Milaeva. "Oxidative activity of organometallic compounds in relation to the coenzymes NADH and NADPH". . p. 907 - 911. Retrieved 1999.
• 2、 Meulenberg, Rogier,Pepi, Milva,De Bont, Jan A.M.. "Degradation of 3-nitrophenol by Pseudomonas putida B2 occurs via 1,2,4-benzenetriol". . p. 303 - 311. Retrieved 1996.
• 3、 Arteel, Gavin E.,Briviba, Karlis,Sies, Helmut. "Function of thioredoxin reductase as a peroxynitrite reductase using selenocystine or ebselen". . p. 264 - 269. Retrieved 1999.
• 4、 Rickus, Jenna L.,Chang, Pauline L.,Tobin, Allan J.,Zink, Jeffrey I.,Dunn, Bruce. "Photochemical coenzyme regeneration in an enzymatically active optical material". . p. 9325 - 9332. Retrieved 2004.
• 5、 Kulishova, Liliya,Dimoula, Kerasina,Jordan, Max,Wirtz, Astrid,Hofmann, Diana,Santiago-Schuebel, Beatrix,Fitter, Joerg,Pohl, Martina,Spiess, Antje C.. "Factors influencing the operational stability of NADPH-dependent alcohol dehydrogenase and an NADH-dependent variant thereof in gas/solid reactors". experimental part. p. 271 - 283. Retrieved 2011/02/22.