Malathion α-Monoacid

Base Information

• Chemical Name: Malathion α-Monoacid
• CAS No.: 1190-29-0
• Molecular Formula: C8H15 O6 P S2
• Molecular Weight: 302.309
• Mol file: 1190-29-0.mol

Synonyms:Butanedioicacid, [(dimethoxyphosphinothioyl)thio]-, 4-ethyl ester (9CI); Succinic acid, mercapto-,4-ethyl ester, S-ester with O,O-dimethyl phosphorodithioate (7CI,8CI);Phosphorodithioic acid, O,O-dimethyl ester, S-ester with 4-ethylmercaptosuccinate (8CI); Malathion monoacid; Malathion a-monoacid; Malathion a-monocarboxylic acid; O,O-DimethylS-(1-carboxy-2-carbethoxy)ethyl phosphorodithioate

Chemical Property of Malathion α-Monoacid

Chemical Property:

• Vapor Pressure: 1.08E-07mmHg at 25°C
• Boiling Point: 405°C at 760 mmHg
• Flash Point: 198.7°C
• PSA: 149.26000
• Density: 1.388g/cm³
• LogP: 2.29390

Purity/Quality:

98%,99%, ^*data from raw suppliers

Malathionα-Monoacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A major biodegradation product of Malathion (M111000).

Technology Process of Malathion α-Monoacid

There total 3 articles about Malathion α-Monoacid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

[(dimethoxyphosphinothioyl)thio]-butanedioic acid, diethyl ester (121-75-5) → malathion alpha-dicarboxylic acid (1190-28-9) + (E)-4-ethoxy-4-oxobut-2-enoic acid (2459-05-4) + S-(1,2-dicarboethoxyethyl)O,S-dimethyl phosphorodithioate (3344-12-5) + malathion monocarboxylic acid (1190-29-0) + oxallic acid isobutyle nonyl ester + Diethyl maleate (141-05-9)

Guidance literature:

With carboxylesterase from Escherichia coli IES-02; In aq. phosphate buffer; at 37 ℃; for 1h; pH=7.5; Catalytic behavior; Enzymatic reaction;

DOI:10.1016/j.ijbiomac.2019.12.192

Reference yield:

malonic acid monoethyl ester (2459-05-4,3249-53-4,3990-03-2) + O,O-dimethyl phosphorodithioic acid (756-80-9) → malathion monocarboxylic acid (1190-29-0)

Guidance literature:

at 55 - 75 ℃; for 8h;

Reference yield:

→ malathion monocarboxylic acid (1190-29-0)

Guidance literature:

entspr. Dithiophosphorsaeure, Ethylhydrogenmaleat/Triphenylbenzoazomethan/h*ν;

DOI:10.1021/jf60202a043

upstream raw materials:

[(dimethoxyphosphinothioyl)thio]-butanedioic acid, diethyl ester

malonic acid monoethyl ester

O,O-dimethyl phosphorodithioic acid

Refernces

• 1、 -. "Malathion hapten, artificial antigen and preparation method thereof (by machine translation)". Paragraph 0099-0102; 0105. . Retrieved 2020/05/01.