N,N-Dimethyl-2-(6-methyl-2-(p-tolyl)imidazo[1,2-a]pyridin-3-yl)acetamide 2,3-dihydroxysuccinate

Base Information

• Chemical Name: N,N-Dimethyl-2-(6-methyl-2-(p-tolyl)imidazo[1,2-a]pyridin-3-yl)acetamide 2,3-dihydroxysuccinate
• CAS No.: 99294-93-6
• Molecular Formula: 2(C19H21N3O)^.C4H6O6
• Molecular Weight: 764.86
• Hs Code.: 2933996500
• European Community (EC) Number: 629-694-9
• ChEMBL ID: CHEMBL1723343
• Mol file: 99294-93-6.mol

Synonyms:Ambien;Amsic;Bikalm;Dalparan;Imidazo(1,2-a)pyridine-3-acetamide, N,N,6-trimethyl-2-(4-methylphenyl)-;N,N,6-trimethyl-2-(4-methylphenyl)imidazo(1,2a)pyridine-3-acetamide hemitartrate;SL 80.0750;SL 800750 23 N;SL-800750-23-N;Stilnoct;Stilnox;zodormdura;Zoldem;Zolirin;Zolpi Lich;Zolpi-Lich;zolpidem;Zolpidem 1A Pharma;Zolpidem AbZ;Zolpidem Hemitartrate;zolpidem tartrate;Zolpimist;Zolpinox

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Chemical Property of N,N-Dimethyl-2-(6-methyl-2-(p-tolyl)imidazo[1,2-a]pyridin-3-yl)acetamide 2,3-dihydroxysuccinate

Chemical Property:

• Appearance/Colour: White to off-white crystalline powder
• Melting Point: 196oC /Zolpidem/
• PSA: 152.67000
• LogP: 1.12620
• Storage Temp.: 2-8°C
• Solubility.: Slightly soluble in water, sparingly soluble in methanol, practically insoluble in methylene chloride.
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 6
• Exact Mass: 457.18490021
• Heavy Atom Count: 33
• Complexity: 551

Purity/Quality:

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi,T,F
• Statements: 36/37/38-39/23/24/25-23/24/25-11
• Safety Statements: 26-36-45-36/37-16-7

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)C2=C(N3C=C(C=CC3=N2)C)CC(=O)N(C)C.C(C(C(=O)O)O)(C(=O)O)O
• Recent EU Clinical Trials: A placebo controlled double blind randomised controlled proof of concept study of zolpidem for the treatment of motor and cognitive deficits in late-stage Parkinson’s
• Clinical Use: Insomnia (short-term treatment)
• Drug interactions: Potentially hazardous interactions with other drugs Antibacterials: metabolism accelerated by rifampicin. Antidepressants: increased sedative effects with sertraline. Antipsychotics: enhanced sedative effects. Antivirals: concentration increased by ritonavir (risk of extreme sedation and respiratory depression) - avoid concomitant use.