1,2-Decanediol

Base Information

• Chemical Name: 1,2-Decanediol
• CAS No.: 1119-86-4
• Molecular Formula: C10H22O2
• Molecular Weight: 174.283
• Hs Code.: 29053995
• European Community (EC) Number: 214-288-2
• NSC Number: 28662
• UNII: S57M60MI88
• DSSTox Substance ID: DTXSID601009388
• Nikkaji Number: J80.156I
• Wikidata: Q27288644
• RXCUI: 1426901
• Mol file: 1119-86-4.mol

Synonyms:1,2-decanediol

Chemical Property of 1,2-Decanediol

Chemical Property:

• Appearance/Colour: White powder
• Vapor Pressure: 0.00254mmHg at 25°C
• Melting Point: 48 °C
• Refractive Index: 1.456
• Boiling Point: 254.999 °C at 760 mmHg
• PKA: 14.48±0.20(Predicted)
• Flash Point: 122.41 °C
• PSA: 40.46000
• Density: 0.922 g/cm³
• LogP: 2.09020
• Storage Temp.: -20°C Freezer
• Solubility.: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
• Water Solubility.: 579mg/L at 20℃
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 8
• Exact Mass: 174.161979940
• Heavy Atom Count: 12
• Complexity: 83.9

Purity/Quality:

98% ^*data from raw suppliers

1,2-Decanediol ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Other Classes -> Alcohols and Polyols, Other
• Canonical SMILES: CCCCCCCCC(CO)O
• Uses: 1,2-Decanediol is a 1,2-alkanediol that is used as an antimicrobial agent in cosmetics. It also suppresses the fluidity of the hydrophilic and hydrophobic groups in the phospholipid membrane of liposomes. Preparation of 1-decene by deoxygenation of 1,2-decanediol with formic acid. It is used to Synthesis of EDOT-C8.

Technology Process of 1,2-Decanediol

There total 49 articles about 1,2-Decanediol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

1-Decene (872-05-9,17438-89-0,25189-70-2) → 1,2-decanediol (1119-86-4)

Guidance literature:

With 4-methylmorpholine N-oxide; dendritic osmium catalyst; In hexane; acetonitrile; tert-butyl alcohol; at 20 ℃; for 36h;

DOI:10.1039/b401994f

Reference yield: 96.0%

3-Octyl-1,3,4,6-tetrahydro-benzo[f][1,4]dioxocine (127392-16-9) → 1,2-decanediol (1119-86-4)

Guidance literature:

With hydrogen; palladium hydroxide - carbon; In ethanol; under 760 Torr;

Reference yield: 95.0%

S-methyl 2-hydroxydecanethioate (124838-42-2) → 1,2-decanediol (1119-86-4)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 3h; Heating;

DOI:10.1246/bcsj.62.2013

upstream raw materials:

1,2-Epoxydecane

Peroxyformic acid

1-Decene

acetic acid

Downstream raw materials:

decan-2-ol

1-Decanol

1-Decene

nonanoic acid

Refernces

• 1、 Masaoka,Sakakibara,Mori. "Synthesis and absolute configuration of (+)-8-hydroxy-hexadecanoic acid, an endogenous inhibitor for spore germination in Lygodium japonicum". . p. 2319 - 2324. Retrieved 1982.
• 2、 Balagam, Bharathi,Mitra, Ranjan,Richardson, David E.. "Osmium-catalyzed asymmetric dihydroxylation by carbon dioxide-activated hydrogen peroxide and N-methylmorpholine". . p. 1071 - 1075. Retrieved 2008.
• 3、 Nikishin,G.I. et al.. "-". . . Retrieved 1966.
• 4、 Fujita, Ken-Ichi,Inoue, Kensuke,Tsuchimoto, Teruhisa,Yasuda, Hiroyuki. "Homogeneous dihydroxylation of olefins catalyzed by OsO4 2- immobilized on a dendritic backbone with a tertiary nitrogen at its core position". . p. 1594 - 1598. Retrieved 2012.
• 5、 Nagayama, Satoshi,Endo, Masahiro,Kobayashi, Shu. "Microencapsulated Osmium Tetraoxide. A New Recoverable and Reusable Polymer-Supported Osmium Catalysts for Dihydroxylation of Olefins". . p. 6094 - 6095. Retrieved 1998.
• 6、 Wen, Haimeng,Xie, Jingyan,Zhou, Yang,Zhou, Yu,Wang, Jun. "Straightforward synthesis of MTW-type magnesium silicalite for CO2 fixation with epoxides under mild conditions". . p. 5725 - 5735. Retrieved 2019.
• 7、 Minato, Makoto,Yamamoto, Keiji,Tsuji, Jiro. "Osmium Tetraoxide Catalyzed Vicinal Hydroxylation of Higher Olefins by Using Hexacyanoferrate(III) Ion as a Cooxidant". . p. 766 - 768. Retrieved 1990.
• 8、 -. "1. 2 - O-alcohol synthetic method of the compound (by machine translation)". Paragraph 0032; 0033. . Retrieved 2019/03/17.