Phthalylsulfacetamide

Base Information

• Chemical Name: Phthalylsulfacetamide
• CAS No.: 131-69-1
• Deprecated CAS: 8048-28-0,1331208-62-8
• Molecular Formula: C16H14 N2 O6 S
• Molecular Weight: 362.363
• Hs Code.: 2935009090
• European Community (EC) Number: 205-035-7
• NSC Number: 759234,163977,4368
• UNII: 24PUW23GRX
• DSSTox Substance ID: DTXSID9059620
• Nikkaji Number: J5.565D
• Wikidata: Q27253867
• NCI Thesaurus Code: C80789
• ChEMBL ID: CHEMBL2106951
• Mol file: 131-69-1.mol

Synonyms:PHTHALYLSULFACETAMIDE;131-69-1;Tamid;Enterosulfamid;Enterosulfon;Ftalicetimida;Talicetimida;Enterocid;Sulphalyl;Talsigel;Thalocid;Phthalylsulphacetamide;Enterosulphamid;Sterathal;Talasulfa;Talsutin;Thalajen;Thalamyd;Thalisul;Kalacet;Rabalan;Talecid;Phthaloylsulfacetamide;4'-(Acetylsulfamoyl)phthalanilic acid;Phthalylsulfacetamid;Phthalylsulfacetimide;Phthalylthioacetamide;Enteramide;TSC-80;N-(o-Carboxybenzoyl)sulfacetamide;2-[[4-(acetylsulfamoyl)phenyl]carbamoyl]benzoic acid;Benzoic acid, 2-[[[4-[(acetylamino)sulfonyl]phenyl]amino]carbonyl]-;TSC-80 Medicated;C16H14N2O6S;Phthalanilic acid, 4'-(acetylsulfamoyl)-;Phthalylsulfanilazetamid;4'-(Acetylsulfamyl)phthalanilic acid;UNII-24PUW23GRX;NSC 163977;NSC-163977;24PUW23GRX;2-((4-(N-Acetylsulfamoyl)phenyl)carbamoyl)benzoic acid;Phthalylsulfacetamide [BAN:NF];N(sup1)-Acetyl-N(sup4)-phthalylsulfanilamide;EINECS 205-035-7;NSC163977;AI3-24457;2-[({4-[(acetylamino)sulfonyl]phenyl}amino)carbonyl]benzoic acid;N-(4-(Acetylsulphamoyl)phenyl)phthalamic acid;2-([(4-([Acetylamino]sulfonyl)phenyl)amino]carbonyl)benzoic acid;SR-01000254500;2-{[4-(acetylsulfamoyl)phenyl]carbamoyl}benzoic acid;2-[[[4-[(Acetylamino)sulfonyl]phenyl]amino]carbonyl]benzoic acid;Benzoic acid, 2-(((4-((acetylamino)sulfonyl)phenyl)amino)carbonyl)-;Oprea1_188425;Oprea1_615208;SCHEMBL49529;CHEMBL2106951;DTXSID9059620;NSC4368;PHTHALYLSULFACETAMIDE [MI];CHEBI:135528;HMS1613G10;HMS3264J03;Pharmakon1600-01505728;N1-Acetyl-N4-phthalylsulfanilamide;HY-B0967;NSC-4368;C16-H14-N2-O6-S;MFCD00020275;NSC759234;PHTHALYLSULFACETAMIDE [MART.];STK047385;PHTHALYLSULFACETAMIDE [WHO-DD];AKOS000490188;CCG-213977;CS-4452;NSC-759234;BS-14902;Phthalylsulfacetamide, analytical standard;SBI-0207072.P001;SW220058-1;C72280;AB01563234_01;AB01563234_02;N-[p-(o-carboxybenzamido)benzenesulfonyl]acetamide;J-006037;SR-01000254500-1;SR-01000254500-2;SR-01000254500-3;2-(4-(N-acetylsulfamoyl)phenylcarbamoyl)benzoic acid;Q27253867;2-({4-[(Acetylamino)sulfonyl]anilino}carbonyl)benzoic acid;2-((4-[(Acetylamino)sulfonyl]anilino)carbonyl)benzoic acid #;2-[[[4-[(Acetylamino)sulfonyl]phenyl]amino]carbonyl]-benzoic acid;BENZOIC ACID,2-[[[4-[(ACETYLAMINO)SULFONYL]PHENYL]AMINO]CARBONYL]-

Chemical Property of Phthalylsulfacetamide

Chemical Property:

• Melting Point: 196°
• Refractive Index: 1.637
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 138.02000
• Density: 1.478 g/cm3
• LogP: 3.00660
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 1
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 5
• Exact Mass: 362.05725734
• Heavy Atom Count: 25
• Complexity: 619

Purity/Quality:

98%,99%, ^*data from raw suppliers

Phthalylsulfacetamide analytical standard ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)NS(=O)(=O)C1=CC=C(C=C1)NC(=O)C2=CC=CC=C2C(=O)O
• Uses: antibacterial

Technology Process of Phthalylsulfacetamide

There total 1 articles about Phthalylsulfacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phthalic anhydride (85-44-9) + sulphaacetamide (144-80-9) → phthalylsulfacetamide (131-69-1,8048-28-0)

Guidance literature:

at 95 ℃; for 1h; Product distribution; Kinetics; Rate constant; concentration, particle size, time dependence;

DOI:10.1002/jps.2600730810

upstream raw materials:

phthalic anhydride

sulphaacetamide

Refernces

• 1、 Fukuoka,Makita,Yamamura,Yoshihashi. "Solid-state reaction between sulfacetamide and phthalic anhydride by grinding". . p. 1342 - 1344. Retrieved 1994.