4,6-Dihydroxynicotinic acid

Base Information

• Chemical Name: 4,6-Dihydroxynicotinic acid
• CAS No.: 5466-62-6
• Molecular Formula: C₆H₅NO₄
• Molecular Weight: 155.11
• Hs Code.: 2933399090
• Mol file: 5466-62-6.mol

Synonyms:2,4-Dihydroxy-5-carboxypyridine;4,6-Dihydroxynicotinic acid;5-Carboxy-4-hydroxy-2-pyridone;NSC 25748;NSC26363;

Chemical Property of 4,6-Dihydroxynicotinic acid

Chemical Property:

• Melting Point: 309-311 °C
• Refractive Index: 1.677
• Boiling Point: 712.615 °C at 760 mmHg
• Flash Point: 384.776 °C
• PSA: 90.65000
• Density: 1.708 g/cm³
• LogP: 0.19100
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

4,6-DihydroxynicotinicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4,6-Dihydroxynicotinic acid

There total 2 articles about 4,6-Dihydroxynicotinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4,6-dihydroxynicotinic acid ethyl ester (6975-44-6) → 4,6-dihydroxy-nicotinic acid (5466-62-6)

Guidance literature:

With potassium hydroxide;

Reference yield:

→ 4,6-dihydroxy-nicotinic acid (5466-62-6)

Guidance literature:

4,6-Dihydroxy-pyridincarbonsaeure-(3)-ethylester, 2n wss. NaOH, Δ;

DOI:10.1039/jr9620003638

Reference yield: 60.0%

4,6-dihydroxy-nicotinic acid (5466-62-6) → 2,4-dihydroxy-3-nitropyridine (89282-12-2)

Guidance literature:

With phosphoric acid; nitric acid; acetic acid; In water;

upstream raw materials:

4,6-dihydroxynicotinic acid ethyl ester

Downstream raw materials:

4,6-dichloropyridine-3-carbonitrile

MB₂₁₈₃₃

2,3,4-pyridinetriamine

2,4-dihydroxy-3-nitropyridine