CID 16219119

Base Information

• Chemical Name: CID 16219119
• CAS No.: 1405-37-4
• Molecular Formula: C25H44N14O7^.H2SO4
• Molecular Weight: 750.78
• Hs Code.: 2941901010
• European Community (EC) Number: 215-776-8
• Mol file: 1405-37-4.mol

Synonyms:1405-37-4;Capreomycin sulfate from Streptomyces capreolus, antibacterial peptide

Chemical Property of CID 16219119

Chemical Property:

• Appearance/Colour: White powder
• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 1376.7 °C at 760 mmHg
• Flash Point: 786.4 °C
• PSA: 458.90000
• LogP: -2.00290
• Storage Temp.: −20°C
• Solubility.: H2O: soluble50mg/mL
• Water Solubility.: Freely soluble in water
• Hydrogen Bond Donor Count: 16
• Hydrogen Bond Acceptor Count: 16
• Rotatable Bond Count: 9
• Exact Mass: 752.29838407
• Heavy Atom Count: 51
• Complexity: 1310

Purity/Quality:

99% ^*data from raw suppliers

Capreomycin sulfate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T
• Hazard Codes: T
• Statements: 61-20/21/22
• Safety Statements: 53-22-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CN=C(NC1C2C(=O)NCC(C(=O)NC(C(=O)NC(C(=O)NC(=CNC(=O)N)C(=O)N2)CNC(=O)C(CCCN)N)CO)N)N.OS(=O)(=O)O
• Isomeric SMILES: C1CN=C(NC1[C@H]2C(=O)NC[C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N/C(=C\NC(=O)N)/C(=O)N2)CNC(=O)[C@H](CCCN)N)CO)N)N.OS(=O)(=O)O
• Description: Capreomycin is a polypeptide antibiotic first isolated from S. capreolus. It is cytotoxic to M. tuberculosis (MIC = 10 μg/ml). Capreomycin is more effective against M. tuberculosis when combined with aminoglycoside antibiotics.
• Uses: antibacterial, tuberculostatic Capreomycin sulfate is a salt of a complex of cyclic pentopeptides isolated from Streptomyces capreolus, first reported in 1962. The sulfate salt is the most commonly accessible formulation of capreomycin and is used for pharmaceutical applications. The complex has two major components, IA and IB, with an exocyclic lysine residue, and two minor delysinyl components, IIA and IIB. Capreomycin is a potent antibiotic with activity against mycobateria, and Gram positive and negative organisms. Capreomycin acts by binding to the 23S ribosomal subunit, disrupting protein synthesis. Thought to inhibit protein synthesis by inhibiting normal ribosomal functions
• Therapeutic Function: Antitubercular