1-[3-(trifluoromethyl)biphenyl-4-yl]azocane

Base Information

• Chemical Name: 1-[3-(trifluoromethyl)biphenyl-4-yl]azocane
• CAS No.: 1198593-80-4
• Molecular Formula: C₂₀H₂₂F₃N
• Molecular Weight: 333.397
• Mol file: 1198593-80-4.mol

Synonyms:1-[3-(trifluoromethyl)biphenyl-4-yl]azocane

Chemical Property of 1-[3-(trifluoromethyl)biphenyl-4-yl]azocane

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 1-[3-(trifluoromethyl)biphenyl-4-yl]azocane

There total 1 articles about 1-[3-(trifluoromethyl)biphenyl-4-yl]azocane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

heptamethyleneimine (1121-92-2) + 4-bromo-3-(trifluoromethyl)biphenyl (876758-59-7) → 1-[3-(trifluoromethyl)biphenyl-4-yl]azocane (1198593-80-4)

Guidance literature:

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; (S)-(1,1'-binaphthalene)-2,2'-diylbis(diphenylphosphine); sodium t-butanolate; In toluene; for 20h; Reflux;

DOI:10.1002/anie.200901986

Reference yield:

1-[3-(trifluoromethyl)biphenyl-4-yl]azocane (1198593-80-4) → C20H23N + 10-phenylazocano[1,2-a]indole (1198594-00-1)

Guidance literature:

With sodium aluminum tetrahydride; niobium pentachloride; In 1,4-dioxane; for 4h; Reflux;

DOI:10.1002/anie.200901986

upstream raw materials:

heptamethyleneimine

4-bromo-3-(trifluoromethyl)biphenyl

Downstream raw materials:

10-phenylazocano[1,2-a]indole

Refernces