D,L-O-DESMETHYLVENLAFAXINE-D6

Base Information

• Chemical Name: D,L-O-DESMETHYLVENLAFAXINE-D6
• CAS No.: 1062605-69-9
• Molecular Formula: C₁₆H₂₅NO₂
• Molecular Weight: 269.332
• Mol file: 1062605-69-9.mol

Synonyms:d6-4-[2-dimethylamino-1-(1-hydroxycyclohexyl)-ethyl]-phenol

Chemical Property of D,L-O-DESMETHYLVENLAFAXINE-D6

Chemical Property:

• Melting Point: 219-221°C
• Flash Point: 9℃
• Storage Temp.: -20°C Freezer
• Solubility.: DMSO (Slightly), Methanol (Slightly, Sonicated)

Purity/Quality:

98%,99%, ^*data from raw suppliers

D,L-O-Desmethylvenlafaxine-d6 ^*data from reagent suppliers

Safty Information:

• Hazard Codes: F,T
• Statements: 11-23/24/25-39/23/24/25
• Safety Statements: 7-16-36/37-45

MSDS Files:

Useful:

• Uses: A deuterated metabolite of Venlafaxine, a selective serotonin noradrenaline reuptake inhibitor. D,L-O-DesMethyl Venlafaxine-d6 can be used as an antidepressant. D,L-O-Desmethyl Venlafaxine-d6, is the labeled analogue of D,L-O-Desmethyl Venlafaxine (D296500), a metabolite of Venlafaxine (V120000).

Technology Process of D,L-O-DESMETHYLVENLAFAXINE-D6

There total 1 articles about D,L-O-DESMETHYLVENLAFAXINE-D6 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

d9-1-[2-dimethylamino-1-(4-methoxyphenyl)-ethyl]-cyclohexanol (940297-30-3) → d6-4-[2-dimethylamino-1-(1-hydroxycyclohexyl)-ethyl]-phenol (1062605-69-9)

Guidance literature:

d9-1-[2-dimethylamino-1-(4-methoxyphenyl)-ethyl]-cyclohexanol; With boron tribromide; In dichloromethane; at -40 - 0 ℃; for 3.5h;

With sodium hydroxide; water; In dichloromethane; at 0 - 20 ℃;

upstream raw materials:

d9-1-[2-dimethylamino-1-(4-methoxyphenyl)-ethyl]-cyclohexanol

Refernces