2-chloroinosine monophosphate

Base Information

• Chemical Name: 2-chloroinosine monophosphate
• CAS No.: 26550-86-7
• Molecular Formula: C₁₀H₁₂ClN₄O₈P
• Molecular Weight: 382.654
• Mol file: 26550-86-7.mol

Synonyms:Inosine,2-chloro-, 5'-(dihydrogen phosphate) (8CI); 2-Chloroinosine 5'-phosphate

Chemical Property of 2-chloroinosine monophosphate

Chemical Property:

• Boiling Point: 850.6°Cat760mmHg
• Flash Point: 468.2°C
• PSA: 189.83000
• Density: 2.39g/cm³
• LogP: -1.49850

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-chloroinosine monophosphate

There total 3 articles about 2-chloroinosine monophosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Guanosine 5'-monophosphate (85-32-5) → 2-Chlor-inosin-5'-phosphat (26550-86-7) + XMP (523-98-8,57282-68-5) + Oxanosine 5'-monophosphate

Guidance literature:

With sodium acetate; sodium chloride; sodium nitrite; In water; at 37 ℃; for 2h; pH=3.2; Product distribution;

DOI:10.1016/S0968-0896(01)00173-0

Reference yield:

→ 2-Chlor-inosin-5'-phosphat (26550-86-7)

Guidance literature:

2-Chlor-inosin, Pyrophosphorylchlorid, m-Kresol;

DOI:10.1021/jo01258a004

Reference yield:

→ 2-Chloroinosinsaeure (26550-86-7)

Guidance literature:

Guanosin-5'-phosphat,CuCl2;

DOI:10.1111/j.1432-1033.1976.tb10363.x

upstream raw materials:

Guanosine 5'-monophosphate

Downstream raw materials:

2-chloroinosine

Refernces

• 1、 Suzuki, Toshinori,Ide, Hiroshi,Yamada, Masaki,Morii, Takashi,Makino, Keisuke. "Formation of 2-chloroinosine from guanosine by treatment of HNO2 in the presence of NaCl". . p. 2937 - 2941. Retrieved 2007/10/03.