8-hydroxy-5-[(1R,2S)-1-hydroxy-2-[(propan-2-yl)amino]butyl]-1,2-dihydroquinolin-2-one

Base Information

• Chemical Name: 8-hydroxy-5-[(1R,2S)-1-hydroxy-2-[(propan-2-yl)amino]butyl]-1,2-dihydroquinolin-2-one
• CAS No.: 72332-33-3
• Molecular Formula: C16H22N2O3
• Molecular Weight: 290.35748
• Hs Code.: 29211190
• European Community (EC) Number: 276-590-0
• Nikkaji Number: J239.392A
• Wikipedia: Procaterol
• Wikidata: Q7247120
• NCI Thesaurus Code: C170351
• Metabolomics Workbench ID: 43522
• ChEMBL ID: CHEMBL1478530
• Mol file: 72332-33-3.mol

Synonyms:(R*,S*)-(+-)-8-Hydroxy-5-(1-hydroxy-2-((1-methylethyl)amino)butyl)-2(1H)-quinolinone;CI 888;CI-888;CI888;Hydrochloride, Procaterol;Monohydrochloride, Procaterol;OPC 2009;OPC-2009;OPC2009;Pro Air;Pro-Air;ProAir;Procaterol;Procaterol Hydrochloride;Procaterol Monohydrochloride;Procaterol Monohydrochloride, (R*,R*)-(+)-Isomer;Procaterol Monohydrochloride, (R*,R*)-(+-)-Isomer;Procaterol Monohydrochloride, (R*,R*)-(-)-Isomer;Procaterol Monohydrochloride, (R*,S*)-(+)-Isomer;Procaterol Monohydrochloride, (R*,S*)-(-)-Isomer;Procaterol, (R*,R*)-(+-)-Isomer;Procaterol, (R*,S*)-(-)-Isomer

Chemical Property of 8-hydroxy-5-[(1R,2S)-1-hydroxy-2-[(propan-2-yl)amino]butyl]-1,2-dihydroquinolin-2-one

Chemical Property:

• Melting Point: 170-173?°C(lit.)
• Boiling Point: 539.5 °C at 760 mmHg
• Flash Point: 280.1 °C
• PSA: 85.35000
• Density: 1.191 g/cm³
• LogP: 2.43460
• Storage Temp.: -20°C
• Solubility.: Acetonitrile (Slightly), Chloroform (Slightly), Methanol
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 290.16304257
• Heavy Atom Count: 21
• Complexity: 397

Purity/Quality:

98%min ^*data from raw suppliers

S- ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC(C(C1=C2C=CC(=O)NC2=C(C=C1)O)O)NC(C)C
• Isomeric SMILES: CC[C@@H]([C@@H](C1=C2C=CC(=O)NC2=C(C=C1)O)O)NC(C)C
• Recent ClinicalTrials: Effect of Oral Procaterol on Postinfectious Persistent Cough
• Recent NIPH Clinical Trials: Holding spacers versus nebulisers for short activated beta-agonist treatment of acute asthma in children
• Description: Like pirbuterol, procaterol exhibits similar broncholytic properties as albuteral, but it has somewhat of a more prolonged action. It is recommended for use as an inhaled drug for treating bronchial asthma.
• Uses: A labelled intermediate of the enantiomer of Florfenicol (F405750), an antibacterial agent.