4-BROMO-3-IODOPHENOL

Base Information

• Chemical Name: 4-BROMO-3-IODOPHENOL
• CAS No.: 202865-84-7
• Molecular Formula: C6H4BrIO
• Molecular Weight: 298.906
• Hs Code.: 2908190090
• Mol file: 202865-84-7.mol

Synonyms:4-BROMO-3-IODOPHENOL;4-Bromo-3-iodophenol 95%;4-Bromo-3-iodophenol95%

Chemical Property of 4-BROMO-3-IODOPHENOL

Chemical Property:

• Boiling Point: 324.4±27.0 °C(Predicted)
• PKA: 8.54±0.18(Predicted)
• PSA: 20.23000
• Density: 2.369±0.06 g/cm3(Predicted)
• LogP: 2.75930

Purity/Quality:

99% ^*data from raw suppliers

4-Bromo-3-iodophenol 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-BROMO-3-IODOPHENOL

There total 2 articles about 4-BROMO-3-IODOPHENOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-iodo-4-methoxybromobenzene (4897-68-1) → 4-bromo-3-iodo-phenol (202865-84-7)

Guidance literature:

With boron dimethyl-trifluoro sulphide; In dichloromethane; for 12h;

DOI:10.1016/j.tet.2008.04.106

Reference yield: 72.0%

3-Iodophenol (626-02-8) → 4-bromo-3-iodo-phenol (202865-84-7)

Guidance literature:

With bromine; In acetic acid; at 20 ℃; for 18h; Inert atmosphere;

DOI:10.1002/chem.201300844

Reference yield: 99.0%

4-bromo-3-iodo-phenol (202865-84-7) + benzyl bromide (100-39-0) → 4-(benzyloxy)-1-bromo-2-iodobenzene

Guidance literature:

With potassium carbonate; sodium iodide; In acetone; at 45 - 50 ℃;

upstream raw materials:

2-iodo-4-methoxybromobenzene

3-Iodophenol

Downstream raw materials:

2-hydroxy-5-phenyl-5H-benzo[b]phosphindole 5-oxide

5-oxido-5-phenyl-5H-benzo[b]phosphindol-2-yl trifluoromethanesulfonate

5-(2-isopropyl-5-methylcyclohexyl)-5-oxido-5H-benzo[b]phosphindol-2-yl trifluoromethanesulfonate

5-(2-isopropyl-5-methylcyclohexyl)-5-oxido-5H-benzo[b]phosphindol-2-yl trifluoromethanesulfonate

Refernces

• 1、 Hickenboth, Charles R.,Rule, Joseph D.,Moore, Jeffrey S.. "Preparation of enediyne-crosslinked networks and their reactivity under thermal and mechanical conditions". . p. 8435 - 8448. Retrieved 2008.