Osthol hydrate

Base Information

• Chemical Name: Osthol hydrate
• CAS No.: 69219-24-5
• Molecular Formula: C15H18O4
• Molecular Weight: 262.30102
• Mol file: 69219-24-5.mol

Synonyms:Osthol hydrate;8-(3-Hydroxy-3-methylbutyl)-7-methoxy-2H-1-benzopyran-2-one

Chemical Property of Osthol hydrate

Chemical Property:

• PSA: 59.67000
• LogP: 2.50510

Purity/Quality:

98.5% ^*data from raw suppliers

Ostholhydrate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Osthol hydrate

There total 2 articles about Osthol hydrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

osthole (484-12-8) → 8-(3-hydroxy-3-methylbutyl)-7-methoxy-2H-chromen-2-one (69219-24-5)

Guidance literature:

osthole; With mercury(II) diacetate; water; In tetrahydrofuran; dichloromethane; for 3h;

With sodium tetrahydroborate; In tetrahydrofuran; dichloromethane;

DOI:10.2174/1573406414666180911161047

Reference yield:

→ 8-(3-hydroxy-3-methylbutyl)-7-methoxy-2H-chromen-2-one (69219-24-5)

Guidance literature:

Osthol-hydrochlorid;

DOI:10.1071/CH9610100

upstream raw materials:

osthole

Refernces

• 1、 Bhunia, Anup,Bergander, Klaus,Daniliuc, Constantin Gabriel,Studer, Armido. "Fe-Catalyzed Anaerobic Mukaiyama-Type Hydration of Alkenes using Nitroarenes". supporting information. p. 8313 - 8320. Retrieved 2021/03/08.
• 2、 Hitotsuyanagi, Yukio,Kojima, Hiroshi,Ikuta, Hiroshi,Takeya, Koichi,Itokawa, Hideji. "Identification and structure-activity relationship studies of osthol, a cytotoxic principle from Cnidium monnieri". . p. 1791 - 1794. Retrieved 2007/10/03.