CK-636

Base Information

• Chemical Name: CK-636
• CAS No.: 442632-72-6
• Molecular Formula: C16H16N2OS
• Molecular Weight: 284.37604
• Mol file: 442632-72-6.mol

Synonyms:CK-636;N-[2-(2-Methyl-1H-indol-3-yl)ethyl]-2-thiophenecarboxamide;CK-0944636;CK-636 N-[2-(2-Methyl-1H-indol-3-yl)ethyl]-2-thiophenecarboxamide;N-[2-(2-Methyl-1H-indol-3-yl)ethyl]-2-thiophenecarboxamide CK636;CK-636, >=98%

Chemical Property of CK-636

Chemical Property:

• PSA: 73.13000
• LogP: 3.90120
• Storage Temp.: 2-8°C
• Solubility.: DMSO: ≥20mg/mL

Purity/Quality:

98% min ^*data from raw suppliers

CK-636 ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 22

MSDS Files:

Useful:

• Description: CK-636 is an Arp2/3 complex inhibitor with IC50 of 4 μM, 24 μM and 32 μM for inhibition of actin polymerization induced by human, fission yeast and bovine Arp2/3 complex, respectively.
• Uses: CK-636 is a small molecule that inhibits Actin-related protein 2/3 (Arp2/3) (1). Arp2/3 is a 7 subunits protein complex that regulates actin cytoskeleton (2). CK-636 interacts with Arp2/3 and prevents actin polymerization.