2-(2-Naphthyl)ethylamine hydrochloride

Base Information

• Chemical Name: 2-(2-Naphthyl)ethylamine hydrochloride
• CAS No.: 2017-67-6
• Molecular Formula: C12H14ClN
• Molecular Weight: 207.7
• Hs Code.: 2921499090
• European Community (EC) Number: 626-331-6
• DSSTox Substance ID: DTXSID80584757
• Mol file: 2017-67-6.mol

Synonyms:2017-67-6;2-(2-Naphthyl)ethylamine hydrochloride;2-(naphthalen-2-yl)ethanamine hydrochloride;2-Naphthalen-2-yl-ethylamine hydrochloride;2-(2-Naphthyl)ethanamine hydrochloride;2-Naphthaleneethanamine HCl;2-Naphthaleneethanamine, hydrochloride (1:1);2-naphthalen-2-ylethanamine;hydrochloride;[2-(2-Naphthyl)ethyl]amine hydrochloride;2-(naphthalen-2-yl)ethan-1-amine hydrochloride;SCHEMBL5169674;DTXSID80584757;VJPPXKBLHHCXLG-UHFFFAOYSA-N;CAA01767;2-naphthaleneethylamine hydrochloride;MFCD08276819;2-naphth-2-ylethylamine hydrochloride;AKOS015995712;SB35166;BS-35829;2-(naphthalen-2-yl)ethanaminehydrochloride;CS-0216260;2-(2-Naphthyl)ethylamine hydrochloride, 97%;EN300-37363;C78028;J-013093;Z381785718;2-(Naphthalen-2-yl)ethan-1-amine--hydrogen chloride (1/1)

Chemical Property of 2-(2-Naphthyl)ethylamine hydrochloride

Chemical Property:

• Melting Point: 226 °C (1st melting event)
• PSA: 26.02000
• LogP: 3.84330
• Storage Temp.: Inert atmosphere,Room Temperature
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 207.0814771
• Heavy Atom Count: 14
• Complexity: 155

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-NaphthaleneethanamineHydrochloride ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 37/38-41
• Safety Statements: 26-36/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C=C(C=CC2=C1)CCN.Cl

Technology Process of 2-(2-Naphthyl)ethylamine hydrochloride

There total 2 articles about 2-(2-Naphthyl)ethylamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

1,8-diazaabicyclo[5.4.0]undec-7-ene + naphthalen-2-ethanol (1485-07-0) → 2-(2-naphthyl)ethylamine hydrochloride (2017-67-6)

Guidance literature:

With diphenylphosphoranyl azide; triphenylphosphine; In tetrahydrofuran; diethyl ether; ethanol; N,N-dimethyl-formamide;

Reference yield:

2-naphthaleneacetonitrile (7498-57-9) → 2-(2-naphthyl)ethylamine hydrochloride (2017-67-6)

Guidance literature:

With hydrogenchloride; sulfuric acid; In 1,4-dioxane;

Reference yield:

C28H38O5Si + 2-(2-naphthyl)ethylamine hydrochloride (2017-67-6) → C38H45NO4Si

Guidance literature:

2-(2-naphthyl)ethylamine hydrochloride; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h; Inert atmosphere;

C₂₈H₃₈O₅Si; In tetrahydrofuran; hexane; for 0.5h; Inert atmosphere;

DOI:10.1021/ol400469w

upstream raw materials:

naphthalen-2-ethanol

2-naphthaleneacetonitrile

Refernces

• 1、 -. "Low molecular weight peptidomimetic growth hormone secretagogues". . . Retrieved 2008/06/13.