Orphenadrine citrate

Base Information

• Chemical Name: Orphenadrine citrate
• CAS No.: 4596-23-0
• Molecular Formula: C₆H₈O₇*C₁₈H₂₃NO
• Molecular Weight: 461.512
• Hs Code.: 2922199090
• Mol file: 4596-23-0.mol

Synonyms:N,N-Dimethyl-2-[(2-methylphenyl)-phenylmethoxy]ethanamine 2-hydroxypropane-1,2,3-tricarboxylic acid salt;Norflex;Orphenadrine citrate;Orphendrine citrate

Chemical Property of Orphenadrine citrate

Chemical Property:

• Vapor Pressure: 1.86E-05mmHg at 25°C
• Boiling Point: 363°C at 760 mmHg
• Flash Point: 107.1°C
• PSA: 144.60000
• LogP: 2.41410

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Hazard Codes: Xi:Irritant
• Statements: R22:; R40:
• Safety Statements: S22:; S36:

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Orphenadrine citrate

There total 2 articles about Orphenadrine citrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

orphenadrine citrate (4682-36-4,4596-23-0) → orphenadrine citrate salt (1202395-79-6,4596-23-0) + orphenadrine citrate salt (1202395-80-9,4596-23-0)

Guidance literature:

With N-(3,5-dichlorophenyl)carbamoyl-derivatized cyclofructan-6 column; In ethanol; n-heptane; at 20 ℃; Resolution of racemate;

DOI:10.1021/ac902257a

Reference yield:

orphenadrine citrate (4682-36-4,4596-23-0) → orphenadrine citrate salt (1202395-79-6,4596-23-0) + orphenadrine citrate salt (1202395-80-9,4596-23-0)

Guidance literature:

With N-(3,5-dichlorophenyl)carbamoyl-derivatized cyclofructan-6 column; In ethanol; n-heptane; at 20 ℃; Resolution of racemate;

DOI:10.1021/ac902257a

upstream raw materials:

orphenadrine citrate

Refernces

• 1、 Sun, Ping,Wang, Chunlei,Breitbach, Zachary S.,Zhang, Ying,Armstrong, Daniel W.. "Development of new HPLC chiral stationary phases based on native and derivatized cyclofructans". experimental part. p. 10215 - 10226. Retrieved 2010/05/01.