9-Fluorenone hydrazone

Base Information

• Chemical Name: 9-Fluorenone hydrazone
• CAS No.: 13629-22-6
• Molecular Formula: C13H10N2
• Molecular Weight: 194.236
• Hs Code.: 2928000090
• European Community (EC) Number: 237-116-8
• NSC Number: 90662,24099
• UNII: D8P2VRA6LZ
• DSSTox Substance ID: DTXSID30159757
• Nikkaji Number: J277.964A
• ChEMBL ID: CHEMBL4069344
• Mol file: 13629-22-6.mol

Synonyms:9-Fluorenone hydrazone;13629-22-6;(9H-Fluoren-9-ylidene)hydrazine;fluoren-9-ylidenehydrazine;9H-Fluoren-9-one, hydrazone;Fluoren-9-one hydrazone;Fluoren-9-one, hydrazone;Fluorenone hydrazone;1-(9H-fluoren-9-ylidene)hydrazine;D8P2VRA6LZ;9H-fluoren-9-ylidenehydrazine;EINECS 237-116-8;NSC-24099;fluoren-9-ylidene-hydrazine;9-FLUORENONEHYDRAZONE;fluorenonhydrazon;UNII-D8P2VRA6LZ;9H-fluoren-9-one hydrazone;SCHEMBL4344205;CHEMBL4069344;DTXSID30159757;HMS1666G16;NSC24099;NSC90662;BBL025622;CCG-44122;MFCD00016357;NSC 24099;NSC 90662;NSC-90662;STL354570;AKOS000400739;CS-0204295;FT-0621652;E85301;11P-072;A807055;J-006829;SR-01000633982-1

Chemical Property of 9-Fluorenone hydrazone

Chemical Property:

• Vapor Pressure: 1.93E-05mmHg at 25°C
• Melting Point: 148-150 °C(lit.)
• Refractive Index: 1.682
• Boiling Point: 362.5 °C at 760 mmHg
• PKA: 0.29±0.20(Predicted)
• Flash Point: 173 °C
• PSA: 38.38000
• Density: 1.23 g/cm³
• LogP: 3.07840
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 194.084398327
• Heavy Atom Count: 15
• Complexity: 248

Purity/Quality:

99% ^*data from raw suppliers

9-FluorenoneHydrazone ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C3=CC=CC=C3C2=NN

Technology Process of 9-Fluorenone hydrazone

There total 17 articles about 9-Fluorenone hydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

9-fluorenone (486-25-9,952573-42-1) → fluoren-9-ylidene-hydrazine (13629-22-6)

Guidance literature:

With hydrazine hydrate; In ethanol; for 15h; Reflux;

DOI:10.1002/anie.201902636

Reference yield: 78.0%

9-(tropylidenehydrazono)fluorene (205757-13-7) → di-fluoren-9-ylidene-hydrazine (2071-44-5) + fluoren-9-ylidene-hydrazine (13629-22-6) + 9-(2-aminotropylidenehydrazono)fluorene

Guidance literature:

With hydrazine hydrate; In pyridine; at 50 ℃; for 12h;

DOI:10.1246/bcsj.71.693

Reference yield: 74.0%

9-fluorenone (486-25-9,952573-42-1) → di-fluoren-9-ylidene-hydrazine (2071-44-5) + fluoren-9-ylidene-hydrazine (13629-22-6)

Guidance literature:

With sodium acetate; hydrazinium sulfate; In methanol; water; for 0.5h; Yields of byproduct given; Heating;

DOI:10.1002/hlca.19850680534

upstream raw materials:

9-fluorenone

ethanol

fluoren-9-ylidene-triethylphosphoranylidene-hydrazine

(diethyl-phenyl-phosphoranylidene)-fluoren-9-ylidene-hydrazine

Downstream raw materials:

9H-fluorene

ammonia

9-diazofluorenone

di-fluoren-9-ylidene-hydrazine

Refernces

• 1、 Agarwal, Nipanshu,Banothu, Venkanna,Kaminsky, Werner,Kollipara, Mohan Rao,Poluri, Krishna Mohan,Shadap, Lathewdeipor. "Fluorenone Schiff base derivative complexes of ruthenium, rhodium and iridium exhibiting efficient antibacterial activity and DNA-binding affinity". . . Retrieved 2020.
• 2、 Bethell, Donald,McDowall, Linda J.,Parker, Vernon D.. "INTERMEDIATES IN THE DECOMPOSITION OF ALIPHATIC DIAZO-COMPOUNDS. PART 20. KINETIC STUDIES ON REDUCTIVELY INITIATED ELECTRON TRANSFER CHAIN CATALYSIS OF THE DECOMPOSITION OF 9-DIAZOFLUORENE". . p. 1531 - 1536. Retrieved 1984.
• 3、 McDowell, Linda J.,Khodaei, M. Mehdi,Bethell, Donald. "The decomposition of diazo-compounds induced by nucleophiles. The decomposition of 9-diazofluorene in the presence of hydroxide or alkoxide ions". . p. 995 - 1003. Retrieved 2003.
• 4、 Chiou, Yi-Ru,Yan, Hongbin,Wan, Chin‐Feng,Yen Huang, Chi,Wu, An-Tai. "A Schiff-based fluorescence sensor for the detection of Cu2+ and its application in living cells". . . Retrieved 2020.
• 5、 Eda,N. et al.. "-". . p. 2431 - 2432. Retrieved 1978.
• 6、 Gazis, Theodore A.,Dasgupta, Ayan,Hill, Michael S.,Rawson, Jeremy M.,Wirth, Thomas,Melen, Rebecca L.. "Reactions of hydrazones and hydrazides with Lewis acidic boranes". supporting information. p. 12391 - 12395. Retrieved 2019/08/26.