METHYL 2-HYDROXYTRICOSANOATE

Base Information

• Chemical Name: METHYL 2-HYDROXYTRICOSANOATE
• CAS No.: 118745-41-8
• Molecular Formula: C24H48O3
• Molecular Weight: 384.643
• Mol file: 118745-41-8.mol

Synonyms:2-HYDROXY C23:0 METHYL ESTER;METHYL 2-HYDROXYTRICOSANOATE

Chemical Property of METHYL 2-HYDROXYTRICOSANOATE

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 412.856°C at 760 mmHg
• PKA: 13.03±0.20(Predicted)
• Flash Point: 192.01°C
• PSA: 46.53000
• Density: 0.903g/cm³
• LogP: 7.34220

Purity/Quality:

95% ^*data from raw suppliers

2-hydroxy Tricosanoic Acid methyl ester ≥98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of METHYL 2-HYDROXYTRICOSANOATE

There total 5 articles about METHYL 2-HYDROXYTRICOSANOATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methanol (67-56-1) + (R)-2-Hydroxy-docosanoic acid [(1S,2S,3R)-2,3-dihydroxy-1-((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxymethyl)-heptadecyl]-amide → methyl D-glucopyranoside (97-30-3,617-04-9,709-50-2,1824-94-8,2152-78-5,3396-99-4,6819-48-3,18469-06-2,20550-04-3,22277-65-2,29411-57-2,35437-40-2,35437-43-5,36191-11-4,36191-12-5,39598-79-3,39598-80-6,39598-89-5,51023-63-3,51223-62-2,51224-38-5,51224-39-6,51224-40-9,51224-41-0,51819-81-9,51819-82-0,51819-83-1,56688-81-4,62279-53-2,64281-79-4,64281-80-7,64912-19-2,66101-73-3,78184-90-4,84368-39-8,84368-40-1,84368-41-2,92142-37-5,93302-26-2,103421-28-9,115794-08-6,3149-68-6) + methyl (2R)-2-hydroxytetracosanoate (2433-95-6,54563-86-9,54563-85-8) + 2R-hydroxydocosanoic acid methyl ester (641637-47-0) + methyl (2R)-2-hydroxytricosanoate (118745-41-8)

Guidance literature:

With hydrogenchloride; for 18h; Further byproducts given;

DOI:10.1002/jlac.199719970629

Reference yield:

methanol (67-56-1) + (2S,3S,4R,9Z)-2-[(2R)-2-hydroxytricosanoylamino]-9-octadecene-1,3,4-triol → C18H37NO3 + methyl (2R)-2-hydroxytricosanoate (118745-41-8)

Guidance literature:

With hydrogenchloride; for 10h; Reflux;

DOI:10.1016/j.fitote.2012.01.008

Reference yield:

methanol (67-56-1) + 1-O-(β-D-glucopyranosyloxy)-(2S,3S,4R,8Z)-2-[(2'R)-2'-hydroxytricosanoylamino]-8-nonadecene-3,4-diol (1280725-63-4) → methyl (2R)-2-hydroxytricosanoate (118745-41-8)

Guidance literature:

With hydrogenchloride; In water; at 80 ℃; for 14h;

DOI:10.1016/j.fitote.2009.08.026

upstream raw materials:

methanol

1-O-(β-D-glucopyranosyloxy)-(2S,3S,4R,8Z)-2-[(2'R)-2'-hydroxytricosanoylamino]-8-nonadecene-3,4-diol

1-O-β-D-glucopyranosyl-(2S,3S,4R,10E)-2-[(2'R)-2'-hydroxytricosanoyl-amino]-10-octadecene-1,3,4-triol

(2S,3S,4R,2'R)-2-(2'-hydroxytricosanoylamino)nonadecane-1,3,4-triol

Refernces

• 1、 Lee, Sang Hee,Hwang, In Hyun,Kim, Ah Jeong,Choi, Young Ji,Jang, Tae-Su,Osada, Hiruyuki,Ahn, Jong Seog,Na, MinKyun,Lee, Seung Ho. "Isolation of protein tyrosine phosphatase 1B inhibitory constituents from the sclerotia of polyporus umbellatus fries". experimental part. p. 697 - 700. Retrieved 2012/01/02.
• 2、 Chen, Lei,Li, Houquan,Song, Hongtao,Zhang, Guogang. "A new cerebroside from Gynura divaricata". experimental part. p. 517 - 520. Retrieved 2010/06/17.