FLI-06

Base Information

• Chemical Name: FLI-06
• CAS No.: 313967-18-9
• Molecular Formula: C25H30N2O5
• Molecular Weight: 438.5161
• Hs Code.: 29339900
• Mol file: 313967-18-9.mol

Synonyms:FLI-06;1,4,5,6,7,8-Hexahydro-2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-3-quinolinecarboxylic acid cyclohexyl ester;1,4,5,6,7,8-Hexahydro-2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-3-quinolinecarboxylic acid cyclohexyl ester FLI-06

Chemical Property of FLI-06

Chemical Property:

• Boiling Point: 597.5±50.0 °C(Predicted)
• PKA: 0.78±0.70(Predicted)
• PSA: 101.22000
• Density: 1.25±0.1 g/cm3(Predicted)
• LogP: 5.92670
• Storage Temp.: 2-8°C
• Solubility.: DMSO: soluble5mg/mL, clear (warmed)

Purity/Quality:

98% ^*data from raw suppliers

FLI 06 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Description: FLI-06 (313967-18-9) was discovered in a screen designed to monitor the trafficking and processing of a ligand-independent Notch-enhanced GFP reporter. It was found to disrupt the Golgi apparatus in a manner distinct from that of brefeldin A. It inhibited general secretion at a step before exit from the ER which was accompanied by a tubule-to-sheet morphological transition of the ER. Thus FLI-06 is the first small molecule acting at such an early stage in secretory traffic.1
• Uses: FLI-06 is a novel inhibitor of Notch signalling and the early secretory pathway.