D-GALACTOSE 1-[2-(2-AZIDOETHOXY)ETHOXYETHYL]-2,3,4,6-TETRA-O-ACETATE

Base Information

• Chemical Name: D-GALACTOSE 1-[2-(2-AZIDOETHOXY)ETHOXYETHYL]-2,3,4,6-TETRA-O-ACETATE
• CAS No.: 381716-33-2
• Molecular Formula: C20H31N3O11
• Molecular Weight: 505.479
• Hs Code.: 2940000000
• Mol file: 381716-33-2.mol

Synonyms:D-GALACTOSE 1-[2-(2-AZIDOETHOXY)ETHOXYETHYL]-2,3,4,6-TETRA-O-ACETATE;2-[2-(2-AZIDOETHOXY)ETHOXY]ETHYL 2,3,4,6-TETRA-O-ACETYL-D-GALACTOPYRANOSIDE;1-[2-(2-AZIDOETHOXY)ETHOXYETHYL]-2,3,4,6-TETRA-O-ACETYL-D-GALACTOSE;Galactose1-[2-(2-azidoethoxy)ethoxyethyl]-2,3,4,6-tetra-O-acetate;2-[2-(2-Azidoethoxy)ethyl]2,3,4,6-Tetra-O-acetyl-D-galactopyranoside;1-[2-(2-Azidoethoxy)ethoxyethyl]-2,3,4,6-tetra-O-acetyl-D-galactopyranoside;[2-(2-Azidoethoxy)ethoxy]ethyl 2,3,4,6-tetra-O-acetyl-D-galactopyranoside

Chemical Property of D-GALACTOSE 1-[2-(2-AZIDOETHOXY)ETHOXYETHYL]-2,3,4,6-TETRA-O-ACETATE

Chemical Property:

• Refractive Index: 1.46
• PSA: 182.64000
• LogP: 0.29836
• Solubility.: slightly sol. in Methanol

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-[2-(2-Azidoethoxy)ethoxy]ethyl 2,3,4,6-Tetra-O-acetyl-D-galactopyranoside ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: 2-[2-(2-Azidoethoxy)ethoxy]ethyl 2,3,4,6-Tetra-O-acetyl-D-galactopyranoside (CAS# 381716-33-2) is a stable and sensitive fluorescent probe and applications for lysosome labeling and tracking during apoptosis. As a reactant, 2-[2-(2-Azidoethoxy)ethoxy]ethyl 2,3,4,6-Tetra-O-acetyl-D-galactopyranoside has been used in the preparation of amyloid-β and tau peptide aggregation modulators.

Technology Process of D-GALACTOSE 1-[2-(2-AZIDOETHOXY)ETHOXYETHYL]-2,3,4,6-TETRA-O-ACETATE

There total 1 articles about D-GALACTOSE 1-[2-(2-AZIDOETHOXY)ETHOXYETHYL]-2,3,4,6-TETRA-O-ACETATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.1%

D-galactose pentaacetate (25878-60-8) + 2-[2-(2-azidoethoxy)ethoxy]ethanol (86520-52-7) → 2-[2-(2-azidoethoxy)ethoxy]ethyl-2,3,4,6-tetra-O-acetyl-D-galactopyranoside (381716-33-2)

Guidance literature:

With boron trifluoride diethyl etherate; In dichloromethane; for 6h; Cooling with ice; Inert atmosphere;

Reference yield: 70.0%

(1E,6E)-1-(4-hydroxy-3-methoxyphenyl)-7-(3-methoxy-4-(prop-2-ynyloxy)phenyl)hepta-1,6-diene-3,5-dione (1000878-11-4) + 2-[2-(2-azidoethoxy)ethoxy]ethyl-2,3,4,6-tetra-O-acetyl-D-galactopyranoside (381716-33-2) → C44H53N3O18 (1330528-77-2)

Guidance literature:

With copper(ll) sulfate pentahydrate; sodium L-ascorbate; In tetrahydrofuran; water; tert-butyl alcohol; at 20 ℃; for 12h;

Reference yield: 60.0%

(1E,6E)-1,7-bis(3-methoxy-4-propargyloxyphenyl)hepta-1,6-diene-3,5-dione (1192838-52-0) + 2-[2-(2-azidoethoxy)ethoxy]ethyl-2,3,4,6-tetra-O-acetyl-D-galactopyranoside (381716-33-2) → C67H86N6O30

Guidance literature:

With copper(ll) sulfate pentahydrate; sodium L-ascorbate; In tetrahydrofuran; water; tert-butyl alcohol; at 20 ℃; for 12h;

upstream raw materials:

D-galactose pentaacetate

2-[2-(2-azidoethoxy)ethoxy]ethanol

Downstream raw materials:

C₄₄H₅₃N₃O₁₈

Refernces