StigMasta-4,22-diene-3β,6β-diol

Base Information

• Chemical Name: StigMasta-4,22-diene-3β,6β-diol
• CAS No.: 167958-89-6
• Molecular Formula: C29H48O2
• Molecular Weight: 428.69022
• Mol file: 167958-89-6.mol

Synonyms:StigMasta-4,22-diene-3β,6β-diol;Stigmasta-4,22-diene-3beta,6beta-diol

Chemical Property of StigMasta-4,22-diene-3β,6β-diol

Chemical Property:

• PSA: 40.46000
• LogP: 6.77160

Purity/Quality:

98% ^*data from raw suppliers

Stigmasta-4,22-diene-3beta,6beta-diol ≥98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of StigMasta-4,22-diene-3β,6β-diol

There total 8 articles about StigMasta-4,22-diene-3β,6β-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

(22E)-5β,6β-epoxystigmast-22-en-3β-ol (132746-54-4) → stigmasta-4,22-diene-3β,6β-diol (167958-89-6)

Guidance literature:

With lithium bromide; In N,N-dimethyl acetamide; for 0.5h; Heating;

Reference yield:

acetic acid stigmasteryl ester (4651-48-3,4651-49-4,54482-54-1,75082-06-3,80735-62-2) → stigmasta-4,22-diene-3β,6β-diol (167958-89-6)

Guidance literature:

Multi-step reaction with 2 steps

1: benzene; SeO₂; aqueous acetic acid / Erhitzen des Reaktionsprodukts mit Acetanhydrid

2: Eindampfen und Kochen des Rueckstands der Mutterlage mit aethanol. KOH

With selenium(IV) oxide; acetic acid; benzene;

DOI:10.1021/ja01272a025

Reference yield:

acetic acid stigmasteryl ester (4651-48-3,4651-49-4,54482-54-1,75082-06-3,80735-62-2) → stigmasta-4,22-diene-3β,6β-diol (167958-89-6) + stigmastadiene-(5,22t)-diyl-(3β,4β)-diacetate

Guidance literature:

With selenium(IV) oxide; acetic acid; benzene; Erhitzen des Reaktionsprodukts mit Acetanhydrid;

DOI:10.1021/ja01272a025

upstream raw materials:

acetic acid stigmasteryl ester

(22E)-5β,6β-epoxystigmast-22-en-3β-ol

selenium(IV) oxide

stigmasterol

Refernces

• 1、 Centurion, Osvaldo M. Teme,Galagovsky, Lydia R.,Gros, Eduardo G.. "Cleavage reaction of 5β,6β steroidal epoxides carrying different groups at C-3". . p. 504 - 508. Retrieved 2007/10/03.