NVP-BVU 972

Base Information

• Chemical Name: NVP-BVU 972
• CAS No.: 1185763-69-2
• Molecular Formula: C20H16N6
• Molecular Weight: 340.38124
• Mol file: 1185763-69-2.mol

Synonyms:NVP-BVU 972;NVP-BVU972;6-[[6-(1-Methyl-1H-pyrazol-4-yl)imidazo[1,2-b]pyridazin-3-yl]methyl]quinoline

Chemical Property of NVP-BVU 972

Chemical Property:

• PKA: 4.92±0.10(Predicted)
• PSA: 60.90000
• Density: 1.35
• LogP: 3.26880
• Solubility.: insoluble in H2O; ≥17 mg/mL in DMSO; ≥25.15 mg/mL in EtOH

Purity/Quality:

98% min ^*data from raw suppliers

NVP-BVU972 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: NVP-BVU972 exhibits strong inhibition towards MET kinase but displays low inhibition against other kinases including the most closely related kinase RON.

Technology Process of NVP-BVU 972

There total 1 articles about NVP-BVU 972 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(rac)-[6-(1-methyl-1H-pyrazol-4-yl)-imidazo[1,2-b]pyridazin-3-yl]-quinolin-6-yl-methanol (1185763-68-1) → NVP-BVU972 (1185763-69-2)

Guidance literature:

With iodine; hypophosphorous acid; acetic acid; In water; at 150 ℃; for 0.5h; Microwave irradiation;

upstream raw materials:

(rac)-[6-(1-methyl-1H-pyrazol-4-yl)-imidazo[1,2-b]pyridazin-3-yl]-quinolin-6-yl-methanol

Refernces