Technology Process of 1,7-Bis(4-hydroxyphenyl)hept-1-en-3-one
There total 9 articles about 1,7-Bis(4-hydroxyphenyl)hept-1-en-3-one which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride;
In
methanol; water;
Reflux;
DOI:10.1021/np500396y
- Guidance literature:
-
Multi-step reaction with 7 steps
1: N-ethyl-N,N-diisopropylamine / dichloromethane / 9 h / 0 - 20 °C
2: lithium aluminium tetrahydride / tetrahydrofuran / -78 °C / Inert atmosphere
3: manganese(IV) oxide / dichloromethane / 48 h / 20 °C
4: sodium hydroxide / water / 16 h / 0 - 20 °C
5: palladium 10% on activated carbon; hydrogen; diphenyl sulfide / chloroform / 24 h / 20 °C
6: sodium hydroxide / ethanol / 20 °C
7: hydrogenchloride / methanol; water / Reflux
With
hydrogenchloride; manganese(IV) oxide; lithium aluminium tetrahydride; diphenyl sulfide; palladium 10% on activated carbon; hydrogen; N-ethyl-N,N-diisopropylamine; sodium hydroxide;
In
tetrahydrofuran; methanol; ethanol; dichloromethane; chloroform; water;
4: |Aldol Condensation / 6: |Aldol Condensation;
DOI:10.1021/np500396y
- Guidance literature:
-
Multi-step reaction with 6 steps
1: lithium aluminium tetrahydride / tetrahydrofuran / -78 °C / Inert atmosphere
2: manganese(IV) oxide / dichloromethane / 48 h / 20 °C
3: sodium hydroxide / water / 16 h / 0 - 20 °C
4: palladium 10% on activated carbon; hydrogen; diphenyl sulfide / chloroform / 24 h / 20 °C
5: sodium hydroxide / ethanol / 20 °C
6: hydrogenchloride / methanol; water / Reflux
With
hydrogenchloride; manganese(IV) oxide; lithium aluminium tetrahydride; diphenyl sulfide; palladium 10% on activated carbon; hydrogen; sodium hydroxide;
In
tetrahydrofuran; methanol; ethanol; dichloromethane; chloroform; water;
3: |Aldol Condensation / 5: |Aldol Condensation;
DOI:10.1021/np500396y