Ammonium-15N chloride

Base Information

• Chemical Name: Ammonium-15N chloride
• CAS No.: 39466-62-1
• Molecular Formula: Cl*H₄N
• Molecular Weight: 54.4848
• Hs Code.: 28459000
• European Community (EC) Number: 684-552-3
• Mol file: 39466-62-1.mol

Synonyms:39466-62-1;Ammonium-15N chloride;azanium;chloride;ammonium-15n-chloride;15N Labeled ammonium chloride;AKOS015903097;Ammonium-15N chloride, 5 atom % 15N;Ammonium-15N chloride, 10 atom % 15N;Ammonium-15N chloride, 60-80 atom % 15N;AMMONIUM CHLORIDE-15N (10 atom % 15N);Ammonium-15N chloride, 92-97.9 atom % 15N;AMMONIUM CHLORIDE-15N (98 ATOM % 15N);Ammonium-15N chloride, >=98 atom % 15N, >=99% (CP)

Chemical Property of Ammonium-15N chloride

Chemical Property:

• Melting Point: 340 °C (subl.)(lit.)
• PSA: 0.00000
• Density: 1.527
• LogP: -2.61980
• Storage Temp.: Inert atmosphere,Room Temperature
• Solubility.: DMSO, Methanol (Sparingly), Water
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 54.0002617
• Heavy Atom Count: 2
• Complexity: 0

Purity/Quality:

98%,99%, ^*data from raw suppliers

Ammonium-15N Chloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22-36
• Safety Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: [NH4+].[Cl-]
• Isomeric SMILES: [15NH4+].[Cl-]
• Recent EU Clinical Trials: An open-label, controlled, multi-site, Phase I clinical trial to assess the ureagenesis capacity in newborns and infants up to the age of 12 months with neonatal and infantile onset of urea cycle disorders (UCD) using a 15N ammonium chloride tracer compared to newborns and infants without UCD.
• Uses: As isotope labelled analogue of Ammonium Chloride, Ammonium chloride-15N can be used in flavouring agents and nitrogen source in fertilizers. Ammonium-15N chloride has been used:as a medium supplement for the incorporation of 15N in sporulation protein, CsfB, for NMR spectroscopyin assaying nitrogen loss in marine sedimentfor the incorporation of 15N in apolipoprotein A-I for mass spectrum analysis

Technology Process of Ammonium-15N chloride

There total 3 articles about Ammonium-15N chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

trans-sodium-vanadium(-I)((15)N2)2(bis(dimethylphosphino)ethane)2 (141521-70-2) → [(15)N]ammonium chloride (39466-62-1,850089-77-9) + [15N2]-hydrazine (29817-79-6)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; bubbling dry HCl gas through THF soln. at -30°C;

Reference yield:

(15)N labeled ammonium sulfate → [(15)N]ammonium chloride (39466-62-1,850089-77-9)

Guidance literature:

With barium(II) chloride; In water; byproducts: BaSO4; 80% (15)N enriched ammonium sulfate in aq. soln. treated with aq. soln. of BaCl2.; BaSO4 was filtered off, washed with water and filtrate evaptd. to dryness.;

Reference yield:

(15)N labeled ammonium sulfate + barium(II) chloride → [(15)N]ammonium chloride (39466-62-1,850089-77-9)

Guidance literature:

In not given; soln. of ((15)NH4)2SO4 with stoich. amt. BaCl2; filtration of pptd. BaSO4, evapn. of filtrate to dryness on steam bath;

upstream raw materials:

trans-sodium-vanadium(-I)(⁽¹⁵⁾N₂)2(bis(dimethylphosphino)ethane)2

Downstream raw materials:

nitrous oxide

dinitrogen monoxide

ammonia

Refernces

• 1、 Appleton, Trevor G.,Hall, John R.,Ralph, Stephen F.. "15N NMR spectra of pentaamminerhodium(III) complexes". . p. 4435 - 4437. Retrieved 2008/10/08.