2,6-Dichloro-4-iodophenol

Base Information

• Chemical Name: 2,6-Dichloro-4-iodophenol
• CAS No.: 34074-22-1
• Molecular Formula: C6H3Cl2IO
• Molecular Weight: 288.9
• Hs Code.: 2908199090
• DSSTox Substance ID: DTXSID20403711
• Nikkaji Number: J2.962.291D
• Wikidata: Q82207460
• Mol file: 34074-22-1.mol

Synonyms:2,6-dichloro-4-iodophenol;34074-22-1;Phenol, 2,6-dichloro-4-iodo-;MFCD00466446;TD1374;C6H3Cl2IO;SCHEMBL2036976;DTXSID20403711;AIGWECICLKWOIR-UHFFFAOYSA-N;2 pound not6-Dichloro-4-iodophenol;AKOS016005751;AB93099;AC-28482;DS-15931;SY034448;CS-0031438;FT-0723074;NS00133707;A875112

Chemical Property of 2,6-Dichloro-4-iodophenol

Chemical Property:

• Melting Point: 91-92 °C
• Boiling Point: 278.2±40.0 °C(Predicted)
• PKA: 6.42±0.23(Predicted)
• PSA: 20.23000
• Density: 2.158±0.06 g/cm3(Predicted)
• LogP: 3.30360
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 287.86057
• Heavy Atom Count: 10
• Complexity: 110

Purity/Quality:

98% purity ^*data from raw suppliers

2,6-Dichloro-4-iodophenol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(C=C(C(=C1Cl)O)Cl)I

Technology Process of 2,6-Dichloro-4-iodophenol

There total 5 articles about 2,6-Dichloro-4-iodophenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

p-Iodophenol (540-38-5) → 2,6-dichloro-4-iodophenol (34074-22-1)

Guidance literature:

With diisobutylamine; sulfuryl dichloride; In toluene; at 20 - 70 ℃; for 1h; Inert atmosphere;

Reference yield: 97.0%

2,6-Dichlorophenol (87-65-0) → 2,6-dichloro-4-iodophenol (34074-22-1)

Guidance literature:

2,6-Dichlorophenol; With ethylenediamine; sodium iodide; In ethanol; water; for 0.25h;

With iodine; In ethanol; water; at 20 ℃;

Reference yield: 80.0%

→ 2,6-dichloro-4-iodophenol (34074-22-1) + 5-<5-(2,6-dichloro-4-iodophenoxy)pentyl>-3-methylisoxazole (107311-60-4)

Guidance literature:

upstream raw materials:

2,6-Dichlorophenol

p-Iodophenol

2-chloro-4-iodophenol

Downstream raw materials:

4-nitro-phenol

(3,5-dichloro-4-hydroxy-phenyl)-oxo-acetic acid methyl ester

2-(3,5-dichloro-4-hydroxyphenyl)-2-oxoethanoic acid

2-(3,5-dichloro-4-isopropoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Refernces

• 1、 -. "DIARYLETHER-BASED FLUOROGENIC PROBES FOR DETECTION OF HYPOCHLOROUS ACID OR HYDROXYL RADICAL". Paragraph 0089; 0090. . Retrieved 2016/11/14.
• 2、 -. "ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF". Paragraph 0339. . Retrieved 2014/11/11.