3-Aminoadipic acid

Base Information

• Chemical Name: 3-Aminoadipic acid
• CAS No.: 40967-78-0
• Molecular Formula: C6H11NO4
• Molecular Weight: 161.16
• Mol file: 40967-78-0.mol

Synonyms:Hexanedioic acid, 3-amino-;

Chemical Property of 3-Aminoadipic acid

Chemical Property:

• Vapor Pressure: 1.13E-06mmHg at 25°C
• Melting Point: 205 °C (dec.)(lit.)
• Refractive Index: 1.515
• Boiling Point: 375.5 °C at 760 mmHg
• Flash Point: 180.9 °C
• PSA: 100.62000
• Density: 1.333 g/cm³
• LogP: 0.35350

Purity/Quality:

99% ^*data from raw suppliers

3-Aminoadipicacid 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 3-Aminoadipic Acid is used to study the structural specificity of the high-affinity uptake of L-glutamate and L-aspartate by rat brain slices.

Technology Process of 3-Aminoadipic acid

There total 23 articles about 3-Aminoadipic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

(S)-3-(((benzyloxy)carbonyl)amino)hexanedioic acid → 3-aminoadipic acid (40967-78-0)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 10h; under 775.743 Torr;

DOI:10.1080/00397911.2020.1802760

Reference yield: 97.0%

(R)-3-(((benzyloxy)carbonyl)amino)hexanedioic acid → D-3-aminohexanedioic acid (40967-78-0)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 10h; under 775.743 Torr;

DOI:10.1080/00397911.2020.1802760

Reference yield:

3-acetylamino-adipic acid (127027-17-2) → 2-aminoadipic acid (5427-96-3,40967-78-0)

Guidance literature:

With hydrogenchloride;

DOI:10.1021/ja01102a024

upstream raw materials:

2-hexenedinitrile

3-amino-adipic acid diethyl ester

3-acetylamino-adipic acid

diethyl 3-oxoadipate

Refernces

• 1、 -. "Peptides with an insulin-like action". . . Retrieved 2008/06/13.
• 2、 Ghislandi,Vercesi. "Optical resolution and configuration of alpha-cyclohexylbenzylamine, of 1,2,3,4-tetrahydro-1-naphthylamine and of 1,2,3,4-tetrahydro-2-naphthylamine". . p. 474 - 486. Retrieved 2007/10/06.