2,3-Dibromopropionyl chloride

Base Information

• Chemical Name: 2,3-Dibromopropionyl chloride
• CAS No.: 18791-02-1
• Molecular Formula: C3H3Br2ClO
• Molecular Weight: 250.317
• Hs Code.: 29159000
• European Community (EC) Number: 242-575-2
• DSSTox Substance ID: DTXSID10940266
• Nikkaji Number: J222.304J
• Mol file: 18791-02-1.mol

Synonyms:2,3-Dibromopropionyl chloride;18791-02-1;2,3-Dibromopropanoyl chloride;Propanoyl chloride, 2,3-dibromo-;2,3-Dibromopropionylchloride;alpha,beta-Dibromopropionyl chloride;EINECS 242-575-2;BRN 1749801;Propionyl chloride, 2,3-dibromo-;3-02-00-00572 (Beilstein Handbook Reference);C3H3Br2ClO;C3-H3-Br2-Cl-O;2,3-dibromopropanyl chloride;SCHEMBL1651416;DTXSID10940266;MFCD00000712;2,3-Dibromopropionyl chloride, 97%;AKOS015900958;AS-12147;Propanoyl chloride, 2,3-dibromo- (9CI);LS-125026;D3288;FT-0637748;D78346;EN300-121881;W-107758

Chemical Property of 2,3-Dibromopropionyl chloride

Chemical Property:

• Vapor Pressure: 0.5mmHg at 25°C
• Refractive Index: n20/D 1.542(lit.)
• Boiling Point: 192 °C at 760 mmHg
• Flash Point: 66.7 °C
• PSA: 17.07000
• Density: 2.209 g/cm³
• LogP: 1.91020
• Sensitive.: Moisture Sensitive
• XLogP3: 2.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 249.82187
• Heavy Atom Count: 7
• Complexity: 75.3

Purity/Quality:

99% ^*data from raw suppliers

2,3-Dibromopropionyl chloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 34-36/37
• Safety Statements: 23-26-27-28-36/37/39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C(C(C(=O)Cl)Br)Br
• Uses: 2,3-Dibromopropionyl chloride was used in synthesis of:series of 2,3-diaminopropionanilidesenantiomers of 1,4-dideoxy-1,4-iminolyxitol and 1,4-dideoxy-1,4-iminoribitolacromelic acid A

Technology Process of 2,3-Dibromopropionyl chloride

There total 3 articles about 2,3-Dibromopropionyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

→ 2,3-dibromo-propionyl chloride (18791-02-1)

Guidance literature:

Reference yield: 88.0%

2,3-dibromopropionic acid (600-05-5) → 2,3-dibromo-propionyl chloride (18791-02-1)

Guidance literature:

With thionyl chloride; In neat (no solvent); reflux, 1 h, room temperature, 24 h;

Reference yield:

acryloyl chloride (814-68-6,25189-84-8) → 2,3-dibromo-propionyl chloride (18791-02-1)

Guidance literature:

With chloroform; bromine;

upstream raw materials:

2,3-dibromopropionic acid

acryloyl chloride

Downstream raw materials:

2,3-dibromo-propionic acid anilide

2,3-dibromo-N-methyl-N-phenylpropanamide

2-[(Z)-Benzylimino]-3-methyl-4-methylene-thiazolidin-5-one

2,3-Dibromo-N-(2-butoxy-phenyl)-propionamide

Refernces

• 1、 -. "A 2, 3 - two bromine propionyl chlorides production process (by machine translation)". Paragraph 0007. . Retrieved 2017/08/28.
• 2、 Tomashevskii, A. A.,Sokolov, V. V.,Potekhin, A. A.. "Reaction of (α-halogenoalkyl)thiiranes with nucleophilic reagents I. Reaction with morpholine". . p. 1610 - 1618. Retrieved 2007/10/03.