2-Methoxy-4-nitrophenol

Base Information Edit

Chemical Name:2-Methoxy-4-nitrophenol
CAS No.:3251-56-7
Molecular Formula:C7H7NO4
Molecular Weight:169.137
Hs Code.:29095000
European Community (EC) Number:221-839-0
NSC Number:26149
UNII:41ITO2N6UT
DSSTox Substance ID:DTXSID4062935
Nikkaji Number:J50.149B
Wikidata:Q27155008
Mol file:3251-56-7.mol

Synonyms:2-Methoxy-4-nitrophenol;3251-56-7;4-Nitroguaiacol;Phenol, 2-methoxy-4-nitro-;3-Nitro-6-hydroxyanisole;Guaiacol, 4-nitro-;2-hydroxy-5-nitroanisole;4-Hydroxy-3-methoxynitrobenzene;Phenol, o-methoxy-p-nitro-;o-Methoxy-p-nitrophenol;4-nitro-2-methoxyphenol;2-methoxy-4-nitro-phenol;Mononitro guaiacol;EINECS 221-839-0;MFCD00012143;NSC 26149;UNII-41ITO2N6UT;BRN 1868796;41ITO2N6UT;AI3-19856;NSC-26149;4-06-00-05627 (Beilstein Handbook Reference);4-Nitrogualacol;NSC26149;4-Nitroguaiacol, 97%;WLN: WNR DQ CO1;2- methoxy- 4- nitrophenol;2-(Methyloxy)-4-nitrophenol;SCHEMBL221924;4-NITROGUAIACOL [INCI];DTXSID4062935;CHEBI:81050;BCP17330;BBL104219;GEO-02006;STL412107;AKOS000282908;3-METHOXY-4-HYDROXYNITROBENZENE;CS-W005249;DS-2084;AC-10540;AM808244;SY004543;LS-104776;FT-0600609;FT-0619233;N0892;EN300-49148;C17386;W-106838;Q27155008;Z415740558

Suppliers and Price of 2-Methoxy-4-nitrophenol

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Nitroguaiacol
10g
$ 130.00

TCI Chemical
4-Nitroguaiacol >98.0%(GC)(T)
5g
$ 22.00

TCI Chemical
4-Nitroguaiacol >98.0%(GC)(T)
25g
$ 66.00

SynQuest Laboratories
2-Methoxy-4-nitrophenol
100 g
$ 228.00

SynQuest Laboratories
2-Methoxy-4-nitrophenol
25 g
$ 77.00

Sigma-Aldrich
4-Nitroguaiacol 97%
5g
$ 90.20

Matrix Scientific
2-Methoxy-4-nitrophenol 97%
1g
$ 47.00

Matrix Scientific
2-Methoxy-4-nitrophenol 97%
10g
$ 210.00

Frontier Specialty Chemicals
4-Nitroguaiacol 97%
25g
$ 253.00

Frontier Specialty Chemicals
4-Nitroguaiacol 97%
5g
$ 77.00

Total 73 raw suppliers

Chemical Property of 2-Methoxy-4-nitrophenol Edit

Chemical Property:

Appearance/Colour:yellow solid
Vapor Pressure:6.26E-05mmHg at 25°C
Melting Point:99-104 °C
Refractive Index:1.5500 (estimate)
Boiling Point:335.2 °C at 760 mmHg
PKA:7.05±0.22(Predicted)
Flash Point:156.5 °C
PSA：75.28000
Density:1.367 g/cm³
LogP:1.83220
Storage Temp.:Refrigerator
Solubility.:Chloroform (Slightly), Ethyl Acetate (Slightly)
Water Solubility.:insoluble
XLogP3:0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:169.03750770
Heavy Atom Count:12
Complexity:167

Purity/Quality:: 4-Nitroguaiacol ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-37/39-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:COC1=C(C=CC(=C1)[N+](=O)[O-])O
Uses A novel 4-nitroguaiacol-degrading actinobacterium. 4-Nitroguaiacol (cas# 3251-56-7) is a compound useful in organic synthesis. Dyes and metabolites.

Technology Process of 2-Methoxy-4-nitrophenol

There total 48 articles about 2-Methoxy-4-nitrophenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 136616-35-8
1-(2-(2-methoxy-4-nitrophenoxy)ethyl)piperidine

: 3251-56-7
2-methoxy-4-nitrophenol

: 3-Methoxy-4-(2-piperidinoethoxy)phenyl 2-piperidinoethyl nitroxide

Guidance literature:: With sodium hydroxide; In water; acetonitrile; for 0.133333h; Ambient temperature; Irradiation;
DOI:10.1021/jo00117a037

Reference yield: 81.0%

: 98996-81-7
2-methoxy-1-(methoxymethoxy)-4-nitrobenzene

: 3251-56-7
2-methoxy-4-nitrophenol

Guidance literature:: With hydrogenchloride; In methanol; dichloromethane; water; at 0 - 20 ℃; for 2.5h;
DOI:10.1021/acsinfecdis.0c00855

Reference yield: 80.0%

: 90-05-1
2-methoxy-phenol

: 3251-56-7
2-methoxy-4-nitrophenol

Guidance literature:: With copper(II) nitrate/zeolite H-Y; for 0.0138889h; Further Variations:; heating mode; times; Product distribution; microwave irradiation;
DOI:10.1080/00397910801982456